Purity
Amount	Crude	Desalted	>75%	>85%	>90%	>95%	>98%
1-4mg	$4.14	$5.31	$8.91	$11.88	$14.22	$15.21	$22.68
5-9mg	$4.86	$6.21	$10.44	$13.95	$16.65	$18.00	$27.00
10-14mg	$5.76	$7.29	$12.24	$16.38	$19.62	$21.15	$31.77
15-19mg	$5.94	$7.47	$13.05	$18.18	$21.69	$23.58	$35.46
20-24mg	$6.39	$7.92	$15.48	$20.34	$23.58	$26.82	$40.32
25-29mg	$6.84	$8.37	$16.83	$21.69	$24.93	$29.35	$43.74
30-39mg	$7.20	$8.73	$18.18	$22.68	$27.27	$31.05	$46.62
40-49mg	$8.10	$9.63	$18.63	$24.03	$28.71	$33.03	$49.77
50-59mg	$8.46	$9.99	$21.33	$26.28	$30.96	$35.28	$52.83
60-79mg	$9.99	$11.52	$24.93	$29.43	$35.28	$40.05	$60.03
80-100mg	$10.35	$11.88	$29.43	$35.28	$42.39	$47.16	$70.65
1000mg	$37.08	$38.61	$88.47	$105.75	$127.08	$141.12	$211.17
*The minimum charge per peptide is $150. *The above prices are per amino acid in the peptide and includes the cost for purification and mass spectrum analysis. *There are no hidden charges. *Please contact us for large scale peptide synthesis quote (from grams to kilograms).

  Applied Biological Materials Inc. is a leading company in custom peptide synthesis. Through innovation, ABM has developed a variety of proprietary technologies thT allow us to provide the highest quality custom synthetic peptides at the most competitive prices. Our custom peptide synthesis offers the following advantages.

No Length Limit

  Whether your peptide is short or long, we can synthesize it for you. For short custom peptides (<50-mer), we synthesize them using our chemical method. For long custom peptides (>50-mer), we synthesize them using our proprietary recombinant peptide technology.

High Quality

  Every single one of our custom peptides is analyzed by Mass Spectrum and HPLC. The quality control data will always be provided to you. We provide proof that your peptides were constructed correctly.

Competitive Pricing

  We will beat any other custom peptide provider's listed price.

Flexibility

  ABM can synthesize any peptide in amounts ranging from milligrams to kilograms (Please ask for quote on amounts >1 gram).

Fast Delivery Time

  For most peptides of 6-30 amino acids in length, our typical turnaround time is about 3 weeks. This time may be extended for certain special peptides due to chemical challenges.

Available Modifications

Terminal Modfications	0-49mg Price	50-499mg Price	500-1000mg Price
Acetylation (N-Terminal)	1a.a.	1a.a.	1a.a.
Acetylation (Lys)	1a.a. + $50	1a.a. + $75	1a.a. + $100
Formylation (N-Terminal)	1a.a. + $50	1a.a. + $75	1a.a. + $100
Fatty acid (N-Terminal)	1a.a. + $50	1a.a. + $75	1a.a. + $100
Myristic acid (N-Terminal)	1a.a. + $50	1a.a. + $75	1a.a. + $100
Palmytolyl (N-Terminal)	1a.a. + $50	1a.a. + $75	1a.a. + $100
Cys(Acm), Cys(tBu)	1a.a. + $50	1a.a. + $75	1a.a. + $100
Benzyloxycarbonylation (CBZ)	1a.a.	1a.a.	1a.a.
Amidation (C-Terminal)	1a.a.	1a.a.	1a.a.
p-Nitroanilide (pNA, C-Terminal)	1a.a. + $85	1a.a. + $115	1a.a. + $150
AMC (C-Terminal)	1a.a. + $125	1a.a. + $185	1a.a. + $250
Succinylation (Suc, N-Terminal)	1a.a. + $15	1a.a. + $22	1a.a. + $30
NHS (OSu, C-Terminal)	1a.a. + $350	1a.a. + $455	1a.a. + $525
CMK/FMK (C-Terminal)	1a.a. + $350	1a.a. + $455	1a.a. + $525
*1.a.a. + $50 means the price for an amino acid in your desired quantity plus an additional $50.
Special Amino Acids	0-49mg Price	50-499mg Price	500-1000mg Price
D-Ile	1a.a. + $75	1a.a. + $112	1a.a. + $150
D-Arg, D-Cys, D-Asp, D-Asn, D-Glu, D-Gln, D-Ser, D-His, D-Thr, D-Trp, D-Lys, D-Tyr, D-Orn, Orn, Abu, Aib, (D)1-Nal, (D)2-Pal, (D)4-Cl-Phe, Nva, Nle, Hse, Hcy, Pen, Mpa	1a.a. + $50	1a.a. + $75	1a.a. + $100
N-Methyl amino acid(Ala, Phe, Leu, Ile, Val, Gly, Met)	1a.a. + $350	1a.a. + $455	1a.a. + $525
D-Ala, D-Leu, D-Met, D-Pro, D-Val, D-Phe, b -Ala, pGlu, Hyp	1a.a. + $25	1a.a. + $35	1a.a. + $50
Other amino acid	Quoted	Quoted	Quoted
Dinitrobenzoylation (Lys)	1a.a. + $125	1a.a. + $185	1a.a. + $250
Lys (Me2)	1a.a. + $125	1a.a. + $185	1a.a. + $250
Phosphorylation (Tyr, Ser, Thr, single site)	1a.a. + $125	1a.a. + $185	1a.a. + $250
Tyr(SO3H2)	1a.a. + $250	1a.a. + $375	1a.a. + $500
Ser(octanoic acid)	1a.a. + $350	1a.a. + $455	1a.a. + $525
Isotype Amino Acid	Quoted	Quoted	Quoted
*1.a.a. + $50 means the price for an amino acid in your desired quantity plus an additional $50.
Fluorescence/Dye Labeling	0-49mg Price	50-499mg Price	500-1000mg Price
Biotin (N-Terminal, Y/N Ahx)	$50	$75	$100
Biotin (Lys in sequence)	$200	$300	$400
Biotin (without Lys in sequence)	1a.a. + $200	1a.a. + $300	1a.a. + $400
FITC/5-FAM (N-Terminal, Y/N Ahx)	$125	$185	$250
Dansyl (N-Terminal, Y/N Ahx)	$125	$185	$250
MCA (N-Terminal)	$125	$185	$250
HYNIC (N-Terminal)	$225	$335	$450
DTPA (N-Terminal)	$225	$335	$450
Quenched Fluorescent Peptide	0-49mg Price	50-499mg Price	500-1000mg Price
Abz/ Tyr (3-NO 2)	$185	$265	$370
EDANS or DABCYL	$300	$450	$600
Cyclic Peptide	0-49mg Price	50-499mg Price	500-1000mg Price
Disulfide Bridge 1st	$200	$300	$400
Disulfide Bridge 2nd	$400	$600	$800
Disulfide Bridge 3rd	$2000	$3000	$4000
Amide cyclic (Side chain, end)	$600	$780	$900
Multiple Antigenic Peptide System	0-49mg Price	50-499mg Price	500-1000mg Price
Asymmetric 4 Branches	$125	$185	$250
Asymmetric 8 Branches	$125	$185	$250
Crude peptide with HPLC analysis, AAA need to add extra cost of $50.
BSA	$125	$185	$250
KLH	$125 (5-10mg)	$140 (11-20mg)	$155 (21-30mg)

How do I dissolve my peptide?

It is vitally important to determine before you order your peptide to determine if it will be soluble in a medium that will be compatible with the experiments you wish to run.

1. Assign a value of -1 to each acidic residue that are Asp (D) and Glu (E) as well as the C-terminal –COOH (not present if peptide is made as an amide).

2. Assign a value of +1 to each basic residue that are Arg (R), Lys (K), His (H), and the N-terminal -NH2 (not present if the peptide was acetylated).

3. Add up the charge, thus determining the overall charge of the peptide.

4. For peptides with an overall charge of 1 or higher (a basic peptide) first try to dissolve the peptide in water. If the peptide does not dissolve, add 10% acetic acid dropwise with vortexing in between. The peptide solution can also be warmed slightly. Longer peptides (20+ amino acids) with a small overall net charge might require the addition of a stronger acid. Trifluoroacetic acid (TFA 10-50ul) is often used to solubilize peptides but it is not cell-friendly and thus is used only if acetic acid fails to help solubilize the peptide. After the addition of TFA, the peptide should be diluted to approximately 1ml with deionized water.

5. For peptides with an overall charge of less than zero (acidic peptide) first try to dissolve the peptide in water. If the peptide does not dissolve, add ammonium hydroxide (NH4OH 10-50ul) and once in solution, dilute the peptide to approximately 1ml with deionized water. Note: Caution must be used, however, with peptides that contain cysteine (C), as the used of alkaline pH can cause disulfide bond formation.

6. For peptides with an overall charge of zero (neutral peptide), solubilization may require the addition of various organic solvents, such as acetonitrile, DMSO, methanol, propanol or isopropanol. Denaturing salts, such as urea or guanidinium-HCL are used as a last resort.

Examples of peptides and their recommended solubilization methods:
o VSRLGGKSIEVKIMPL [+4] + [-2] = +2 A basic peptide – see method #4 above.
o acetyl-VSRLGGKSIEVKIMPL-amide [+3)]+ [-1] = +2 A basic peptide – see method #4 above.
o acetyl-CGDLVGIKRETEYPRLAV [+3] + [-4] = -1 An acidic peptide but given the presence of cysteine, caution should be used. Thus water or a small amount of organic should be tried first.

To summarize:
- if the sequence is basic in nature, then use 10% acetic acid to dissolve.
- if the sequence is acidic in nature, use 0.1 M ammonium bicarbonate to dissolve.
- if both ways above fail, use 20~30% DMSO; it will definitely dissolve.