Custom Recombinant Adenovirus Service
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Service Details
Description
Recombinant adenoviruses are versatile and highly efficient tools used for gene delivery and expression in mammalian cells. Numerous biological features of adenoviruses have made them the vector of choice for both in vitro and in vivo applications. They can infect a broad range of cell types with the highest efficiency. Additionally, their infection is not dependent on active host cell division. Another key feature for recombinant adenovirus is that high virus titers and high-level gene expression can be obtained in most mammalian cells.
ABM produces custom recombinant adenovirus containing full-length cDNA, allowing high level gene expression in host cells or an adenovirus construct containing RNAi oligos specific to a target gene to generate efficient elimination of target gene expression.
ABM produces custom recombinant adenovirus containing full-length cDNA, allowing high level gene expression in host cells or an adenovirus construct containing RNAi oligos specific to a target gene to generate efficient elimination of target gene expression.
Service Selector Assistant
To aid your selection of the service option(s) you will require please use the following...
What would you like to do to your gene?
What would you like to do to your gene?
Service Agreement 
***Please see the service agreement document for additional details and options.***
Vectors
| pShuttle(+) | pShuttle(-) |
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| Click for Details | Click for Details |
| pSiShuttle | pPromoter |
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| Click for Details | Click for Details |
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FAQs
We are interested in expressing a large gene (~9000 bp). Can this gene be expressed using adenovirus and can your company clone the DNA and make the recombinant virus?
It will be challenging for gene over 8.0kb. but we will give it a try and you don't have to pay if the project fails. However, you do need to subclone into our pShuttle vector first or we will do it for an extra charge.
How much pShuttle DNA should I provide for the custom adenovirus service?
We will need the pShuttle DNA concentration somewhere between 0.15ug/ul - 0.5ug/ul and the final amount of DNA to be at least 8ug.
Do you prepare vectors with AAV (adenoassociated virus)?
We currently do not offer AAV service.