iPSC Small Molecules
Induced pluripotent stem cell (iPSC) generation,
a valuablel tool in stem cell research, has traditionally been achieved by the over
expression of four of the six iPSC transcription factors. Recent studies, however,
have shown that some genetic function of these six iPSC transcription factors required
for iPSC generation can be substituted by defined small chemical molecules. Now we
know that some small molecules are the key to directly controlling stem cell development
and could contribute to the advancement of tissue repair and regeneration.
ABM developed and distributes small chemical compunds that have been
shown to play a role in stem cell and iPSC research. All our molecules
are of the highest purity (≥98%), structurally verified by NMR and mass
spectrometry, and tested for cytotoxicity.