Anti-CD117-c-Kit Antibody

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Anti-human CD117 (c-kit) Antibody
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Cat.No.: Y077098
Quantity: 100 μl
Price: $410.00
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Phone: 604-247-2416 (Local), 1-866-757-2414 (Toll free)
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Data Sheet
Print Version
Antibody Type primary antibody
Description mAb name/Clone:57A5

Human CD117 (c-kit) is a transmembrane protein with receptor tyrosine kinase capacity and serves as the receptor for steel factor (SLF). CD117 is expressed on almost all hematopoietic progenitor cells and receptor/ligand interaction is crucial for development of hematopoietic stem cells. Antibody 57A5 recognizes the CD117 molecule of about 150 kd.
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Immunogen Human MO7e tumor cells
Species Reactivity human
Specificity Antibody 57A5 recognizes epitope 2 of the CD117 molecule of about 150 kd.
Tested Applications IP,Flow Cyt,other
Application Notes Antibody 57A5 does not block binding of SCF (4).
Raised In mouse
Clonality Monoclonal
Isotype IgG1
Purity Protein A Purified
Storage Buffer PBS, pH 7.4 with 0.02% sodium azide.
Formulation Liquid
Concentration 1ug/ul
Storage This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
References 1. L.K. Ashman, et al, (1994) J Cellular Physiol 158: 545-554.
2. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 1856, 1882-1888.
3. J.R. Keller, et al, (1995) Blood 86: 1757-1764.
4. Leukocyte Typing VI (T. Kishimoto, et al, eds.) Garland Publishing, Inc., New York (1997) p. 816-818.
Caution Anti-human CD117 (c-kit) Antibody is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
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