Coronavirus/SARS-CoV-2 Receptors


Coronaviruses infect target cells by binding to receptors on the host cell membrane. For this reason, we offer a collection of receptor-related reagents, includes receptor expression vectors, proteins, antibodies, and stable cell lines. In addition, we also offer reagents for other host cell proteins involved in the SARS-CoV-2 infection mechanism.

Angiotensin Converting Enzyme 2 (ACE2)


The Angiotensin converting enzyme 2 (ACE2) is the host cell receptor for SARS-CoV-2 infections, binding to the Spike (S) protein on SARS-CoV-2.


PRODUCTDESCRIPTION
Gene ExpressionORF | Lenti- | Adeno- | AAV | Retro- | Protein Vector
Protein ExpressionProtein Lysate | Recombinant Protein
AntibodiesMonoclonal and Polyclonal
Cell Lines

Transmembrane Serine Protease 2 (TMPRSS2)


Transmembrane Serine Protease 2 (TMPRSS2) facilitates fusion of SARS-CoV-2 with host cell membrane by cleaving and activating the viral spike glycoproteins.


PRODUCTDESCRIPTION
Gene ExpressionORF | Lenti- | Adeno- | AAV | Retro- | Protein Vector
Protein ExpressionProtein Lysate | Recombinant Protein
AntibodiesMonoclonal and Polyclonal
Cell LinesCRISPR TMPRSS2 Knockout Cell Lines

SARS-CoV-2 Spike Protein Pseudotype Lentivirus


Lentivirus products can be packaged with SARS-CoV-2 Spike protein instead of the standard vesicular stomatitis G (VSV-G) envelope glycoprotein to generate S protein pseudotype lentivirus, which can be used to study infection of cells expressing ACE2 (in vitro) or in animal models (in vivo). The Add-on option allows for any of abm’s cataloged or custom lentiviruses to be packaged with the S protein.


PRODUCTDESCRIPTION
Add-on for SARS-CoV-2 S Protein Pseudotype LentivirusC486
SARS-CoV-2 S Protein Pseudotype Lentiviral Packaging MixLV700

Other Related Host Cell Genes


For other Coronavirus related genes that are not listed in the table below, please inquire .


PRODUCTDESCRIPTION
CD209ORF | Lenti- | Adeno- | AAV | Retro- | Protein Vector
DDX39BORF | Lenti- | Adeno- | AAV | Retro- | Protein Vector
DPP4ORF | Lenti- | Adeno- | AAV | Retro- | Protein Vector

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