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Recombinant Human AITRL (TNFSF18)
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|Alternative Names||Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6
Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18)
|Description||TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4Â-CD8Â double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18's expression is transiently up-regulated by proinflammatory stimulation.|
|Molecular Weight||14.2 kDa|
|Endotoxin Level||< 1.0 EU/μg of recombinant protein as determined by the LAL method.|
|Purity||>95% as determined by SDS-PAGE|
|Formulation||Lyophilized from a 0.2 micron filtered solution in Tris and salt|
|Reconstitution||Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human or bovine serum albumin.|
|Storage||The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.|
|Usage||For research use only. Not for diagnostic or therapeutic use.|
· Endotoxin is generally measured in Endotoxin Units per milliliter (EU/mL).
· For recombinant proteins: EU is reported per microgram of protein.
· One EU = 0.1-0.2 ng endotoxin/µg of protein.
· At abm, we do the LAL chromogenic assays that can detect down to 0.01 EU/ml.