Search Growth Factors & Cytokines By Gene Symbol

Recombinant Human AITRL (TNFSF18)


  To order products, check the corresponding boxes on the right and then click on add to cart.
Product Source Size Cat. No. Price
Recombinant Human AITRL (TNFSF18) E. coli30 µg Z101725 $70.00
200 µg Z101727 $410.00
1.0 mg Z101729 $1,890.00
Cat. No. Product Name Qty. Promo/% Off Amount
    Total: $0.00  

Haul in savings with our December-only offers on restriction enzymes, growth factors, PCR products and more! Check in every week of December to unwrap a new gift! Details here:
*Notes about Promo Codes: For NON-DISCOUNT promo codes (i.e. free items or shipping) please enter them during check out in the Notes/Promo Code field. To enter a DISCOUNT promo code enter it into the corresponding box in the 'Promo/% Off' column and then click 'Update' for the given product. If the code is valid for that product the discount percentage will display in place of the box and the amount will become the discounted total for that product(s). If the code is not valid it will remain in the box, please double check the expiry and spelling, and if you feel the code should still be accepted please contact us.
Catalog Number Quantity Promotion Code (Optional)
Data Sheet
Print Version
Alternative Names Activation-inducible TNF-related ligand, AITRL, Glucocorticoid-induced TNF-related ligand, GITRL, hGITRL, Tumor necrosis factor ligand superfamily member 18, TNFSF18, TL-6
Recombinant Human Activation-Induced TNFR Member Ligand (TNFSF18)
Description TNFSF18 is a transmembrane glycoprotein which is expressed in vascular endothelial cells as well as neurons, antigen presenting cells, CD4­-CD8­ double negative thymic precursors, and in the eye. TNFSF18 works to mediate the interactions between T cells and endothelial cells, and T cell growth. It has been shown that TNFSF18's expression is transiently up-regulated by proinflammatory stimulation.
Gene Symbol TNFSF18
Gene ID 8995
Accession No. Q9UNG2
Source E. coli
Appearance Lyophilized Powder
Molecular Weight 14.2 kDa
Endotoxin Level < 1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity >95% as determined by SDS-PAGE
Gel Image Click To Enlarge
Bioactivity N.A.
Bioactivity Data Click To Enlarge
Formulation Lyophilized from a 0.2 micron filtered solution in Tris and salt
Reconstitution Reconstitute at 0.1 mg/mL in PBS containing at least 0.1% human or bovine serum albumin.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Product Documents
Product References
Submit a new question:
How are endotoxin levels measured?
1. For estimating the endotoxin levels; we use the LAL (Limulus Amebocyte Lysate) method: The lysate from horseshoe crab amebocytes clots in the presence of very low endotoxin. This reaction is the basis of the Limulus amebocyte lysate (LAL) assay which was approved by the FDA in 1970.

· Endotoxin is generally measured in Endotoxin Units per milliliter (EU/mL).

· For recombinant proteins: EU is reported per microgram of protein.

· One EU = 0.1-0.2 ng endotoxin/µg of protein.

· At abm, we do the LAL chromogenic assays that can detect down to 0.01 EU/ml.
With regard to the BSA levels in some Growth Factors and Cytokines, can you please provide an explanation as to why they are so high?
The amount of BSA, as part of the formulation of a protein, can vary considerably depending on how much BSA was deemed optimum/necessary for protein stability in combination with /in-lieu of - other possible additives. The aforementioned formulations are somewhat analogous to the “carrier” versions of many formulations from “R and D systems” that have as high as 50 µg of BSA per µg of the recombinant protein product. If, needed or desired, abm scientists can substitute BSA for other stabilizing additives for most formulations.
Are your Escherichia coli sourced growth factors: 1) Human derived materials free? 2) Recombinant proteins free?
Yes, all of abm's growth factors made in Escherichia coli using recombinant technology contain no human derived-products or other recombinant proteins. In the rare cases of BSA presence, this will be mentioned in the product's formulation.
What is the amino acid numbering of this protein?
This protein corresponds to the predicted extracellular domain (amino acid 72-199 inclusive).
What is the BSA concentration in the solution the protein is lyophilized from?
BSA is present at 5µg/µg of the recombinant Growth Factor/cytokine concentration in the lyophilized solution.