Search Growth Factors & Cytokines By Gene Symbol
Recombinant Human FGF20
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Recombinant Human Fibroblast Growth Factor 20 (FGF20)
|Description||FGF-20 is a heparin binding protein of the FGF family which works to control cell division, differentiation, and function. These proteins are especially prominent during prenatal development and postnatal growth. FGF-20 shares a high degree of homology with FGF-9 and FGF-16. The group of receptors which FGF-20 binds to comprises of FGFR1c, FGFR2c, FGFR3b, FGFR3c and FGFR4. It is shown that FGF-20 is found in a variety of cells, including but limited to, dopaminergic neurons, fibroblasts, keratinocytes and breast epithelium.|
|Molecular Weight||23.5 kDa|
|Endotoxin Level||<1.0 EU/μg of recombinant protein as determined by the LAL method.|
|Purity||>95% as determined by SDS-PAGE|
|Bioactivity||Measured in a cell proliferation assay using NR6R-3T3 mouse fibroblast cells|
|Formulation||Lyophilized from a 0.2 μm filtered solution in 10mM MOPS, 10mM ammonium sulphate, 0.2mM DTT and 0.2mM EDTA (pH 7.0).|
|Reconstitution||Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin|
|Storage||The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.|
|Usage||For research use only. Not for diagnostic or therapeutic use.|
· Endotoxin is generally measured in Endotoxin Units per milliliter (EU/mL).
· For recombinant proteins: EU is reported per microgram of protein.
· One EU = 0.1-0.2 ng endotoxin/µg of protein.
· At abm, we do the LAL chromogenic assays that can detect down to 0.01 EU/ml.