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Recombinant Human IGF2BP2
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|Alternative Names||Insulin-like growth factor 2 mRNA-binding protein 2, IGF2 mRNA-binding protein 2, IMP-2, Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, VICKZ family member 2, VICKZ2
Recombinant Human IGF2BP2 (IGF2BP2)
|Description||IGF2 mRNA-binding protein 2 (IGF2BP2), also known as IMP2, was found to be an HMGA2 target gene during early embryonic development. IGF2BP2 belongs to a family of RNA-binding proteins that contain six characteristics of RNA-binding modules, including two N-terminal RNA recognition motifs (RRM1 and RRM2) and four C-terminal hnRNP K-homology (KH1&KH4) domains. Its homolog, IGF2BP1/IMP1, has been shown to be essential for normal embryonic growth and development.|
|Molecular Weight||60.0 kDa|
|Endotoxin Level||<1.0 EU/μg of recombinant protein as determined by the LAL method.|
|Purity||>95% as determined by SDS-PAGE|
|Formulation||Recombinant Human IGF2BP2 is lyophilized from 0.2 μm filtered PBS solution, pH7.2 , 5% Trehalose.|
|Reconstitution||A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.|
|Storage||Recombinant IGF2BP2 can be stored in working aliquots at 2° - 8°C for one month, or at -20°C to -70°C for twelve months. Avoid repeated freeze/thaw cycles.|
|Usage||For research use only. Not for diagnostic or therapeutic use.|
· Endotoxin is generally measured in Endotoxin Units per milliliter (EU/mL).
· For recombinant proteins: EU is reported per microgram of protein.
· One EU = 0.1-0.2 ng endotoxin/µg of protein.
· At abm, we do the LAL chromogenic assays that can detect down to 0.01 EU/ml.