Search Growth Factors & Cytokines By Gene Symbol
Recombinant Human IL36A
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|Alternative Names||IL-1 Epsilon, FIL1 epsilon, Interleukin-1 family member 6, IL-1F6, IL-36 gamma, IL-1F, IL-1H1
Recombinant Human Interleukin-36 alpha (IL36A)
|Description||IL-1 epsilon is an actively secreted member of the IL-1 family of cytokines. It is mainly expressed in tissues with epithelial cells and in psoriatic plaques, as well as by monocytes, B cells and T cells. IL-1 epsilon has been shown to signal through the IL-Rrp2 receptor which is primarily expressed on certain denditic cells, and to act as an agonist of NF-kappaB which then stimulates the inflammatory response in bronchial epithelial cells.|
|Molecular Weight||17.4 kDa|
|Endotoxin Level||<1.0 EU/μg of recombinant protein as determined by the LAL method.|
|Purity||>95% as determined by SDS-PAGE|
|Formulation||Lyophilized from a 0.2 μm filtered solution in PBS, NaCl and Tween® 20 with BSA as a carrier protein|
|Reconstitution||Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin|
|Storage||The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.|
|Usage||For research use only. Not for diagnostic or therapeutic use.|
· Endotoxin is generally measured in Endotoxin Units per milliliter (EU/mL).
· For recombinant proteins: EU is reported per microgram of protein.
· One EU = 0.1-0.2 ng endotoxin/µg of protein.
· At abm, we do the LAL chromogenic assays that can detect down to 0.01 EU/ml.