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Recombinant Human PDGFC
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|Alternative Names||PDGF-C, Fallotein, Spinal cord-derived growth factor, SCDGF, VEGF-E, PDGF-CC
Recombinant Human Platelet-Derived Growth Factor Subunit C (PDGFC)
|Description||PDGF-C plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. It is required for normal skeleton formation and skin morphogenesis during embryonic stage and for angiogenesis and blood vessel development. A disulfide-linked homodimer, PDGF-C also appears to be involved in all the three stages (inflammation, proliferation and remodeling) of wound healing.|
|Molecular Weight||12.5 kDa|
|Endotoxin Level||<1.0 EU/μg of recombinant protein as determined by the LAL method|
|Purity||>95% as determined by SDS-PAGE|
|Formulation||Lyophilized from a 0.2 μm filtered solution in PBS|
|Reconstitution||Reconstitute at 0.1mg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.|
|Storage||The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.|
|Usage||For research use only. Not for diagnostic or therapeutic use.|
· Endotoxin is generally measured in Endotoxin Units per milliliter (EU/mL).
· For recombinant proteins: EU is reported per microgram of protein.
· One EU = 0.1-0.2 ng endotoxin/µg of protein.
· At abm, we do the LAL chromogenic assays that can detect down to 0.01 EU/ml.