|Description||CD44 is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA), and their interaction plays an important role in cell migration, tumor growth and progression. CD44 can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. It may play an important role in invadopodia formation in cancer cell. Altered expression or dysfunction of this protein is shown to cause numerous pathogenic phenotypes.|
|Unit quantity||100 μl|
|Species Reactivity||Human, Other|
|Immunogen||Human lymphoid cells|
|Applications||WB: 1:2000~1:5000 IHC: 1:200~1:500 IF: 1:200~1:500 Optimal dilutions should be calculated by the end user based on their specific application.|
|Recommended Dilutions||WB: 1:2000~1:5000|
Optimal dilutions should be calculated by the end user based on their specific application.
|Storage Condition||This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.|
|Storage Buffer||PBS, pH 7.4 with 0.05% sodium azide|
|Guarantee||abm guarantees that all our Anti-CD44 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.|
|Purity||The antibody was affinity-purified from hybridoma supernatant by affinity-chromatography.|
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