Anti-GAPDH Polyclonal Loading Control Antibody

CAT.NOUNITPRICE
Y058203100 μl
$155.00

Specifications


DescriptionThis gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
SKUY058203
Unit quantity100 μl
CloneRabbit
Raised inRabbit
ClonalityPolyclonal
IsotypeRabbit IgG
Species ReactivityHuman
SpecificityNot yet tested in other species.
ImmunogenSynthetic peptide conjugated to KLH
ApplicationsFor research use onlyPeptide ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1000 Optimal dilutions/concentrations should be determined by the end use.
Recommended DilutionsFor research use onlyPeptide ELISA titer: 1:20,000-1:80,000 Western blot analysis: 1:500-1000 Optimal dilutions/concentrations should be determined by the end use.
FormulationLiquid
Concentration100ug/100ul
Storage ConditionThis product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage BufferPBS, pH 7.4 with 0.02% Sodium Azide
Cellular Localization Cytoplasmic
Guaranteeabm guarantees that all our Anti-GAPDH Polyclonal Loading Control Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
PurityAffinity purified
RelevanceGlyceraldehyde-3-phosphate dehydrogenase catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The enzyme exists as a tetramer of identical chains. A GAPD pseudogene has been mapped to Xp21-p11 and 15 GAPD-like loci have been identified.
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