|Description||Hemagglutinin (HA) is a class I viral fusion protein from Influenza virus. It is a major glycoprotein, comprising over 80% of the envelope proteins present in the virus particle. HA binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell, and is responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. The extent of infection into host organism is determined by HA. In natural infection, inactive HA is matured into HA1 and HA2 outside the cell by one or more trypsin-like, arginine-specific endoproteases secreted by the bronchial epithelial cells. The HA protein is a homotrimer of disulfide-linked HA1-HA2. It also plays a major role in the determination of host range restriction and virulence. Genetic variation of hemagglutinin and/or neuraminidase genes results in the emergence of new influenza strains.
The antibody ab20084 is able to recognise the HA epitope when used to tag other proteins.
|Unit quantity||100 μg|
|Clone||Affinity Purified Polyclonal Antibody|
|Immunogen||HA (YPYDVPDYA) - KLH|
|Applications||Suitable for Western Blot, ELISA and Histochemistry|
|Recommended Dilutions||Suitable for Western Blot, ELISA and Histochemistry|
|Storage Condition||This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.|
|Storage Buffer||PBS,pH 7.2 with 0.1% Sodium Azide|
|Guarantee||abm guarantees that all our Anti-Hemagglutin Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.|
There are no FAQs for this product yet!
There are no references for this product yet!