Anti Human ABAT Polyclonal Antibody

CAT.NOUNITPRICE
Y055360100μl
$385.00

Specifications


Description4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene. [provided by RefSeq, Jul 2008]
SKUY055360
Unit quantity100μl
ClonePolyclonal
Raised inRabbit
ClonalityPolyclonal
IsotypeIgG
Species ReactivityHuman
ImmunogenRecombinant Protein
ApplicationsELISA 1:1,000~100,000 Western blotting 1:100~1,000
Recommended DilutionsELISA 1:1,000~100,000 Western blotting 1:100~1,000
FormulationLiquid
Concentration1ug/ul
Storage ConditionThis product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Storage BufferPBS, pH 7.4 with 0.1% sodium azide, 50% Glycerol
Cellular LocalizationCytoplasmic
Guaranteeabm guarantees that all our Anti Human ABAT Polyclonal Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
PurityAntigen Affinity Purified
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