Anti-Immunoglobulin G1(IgG1) Control, Mouse -PE Antibody
|Description||Immunoglobulin G (IgG), is one of the most abundant protein in human serum with normal levels between 8-17 mg/ml in adult blood. IgG is important for our defence against microorganisms and the molecules are produced by B-lymphocytes as a part of our adaptive immune response. The IgG molecule has two separate functions; to bind to the pathogen that elicited the response and to recruit other cells and molecules to destroy the antigen. The variability of the IgG pool is generated by somatic recombination and the number of specificities in an individual at a given time point is estimated to be 1011 variants.
Of the four human IgG subclass heavy chain (IGHG) genes, three; IGHG1, IGHG2 and IGHG3; have allelic forms which encode antigenic determinants called G1m, G2m and G3m allotypes for markers of the IgG1, IgG2 and IgG3 molecules.
Heavy chain gamma has a constant region composed of three tandem immunoglobulin domains but also have a hinge region for added flexibility. Clone#: CLB-203
|Unit quantity||100 tests|
|Clone||Conjugated Monoclonal Antibody|
|Isotype||Mouse IgG1 PE|
|Specificity||Directed against plant allergens. There is no reactivity with human blood cells and immunoglobulins. Use as a negative control reagent for flow cytometry.|
|Immunogen||Ascites fluid of tumor bearing mice|
|Applications||F/P ratio is 1.0-2.0|
|Recommended Dilutions||F/P ratio is 1.0-2.0|
|Storage Condition||This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.|
|Storage Buffer||20mM Tris with 150mM NaCl, pH8.0.|
|Guarantee||abm guarantees that all our Anti-Immunoglobulin G1(IgG1) Control, Mouse -PE Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.|
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