Anti-Myc (Ab-358) Antibody
| CAT.NO | UNIT | PRICE |
|---|---|---|
| Y021035 | 100 μg | $285.00 |
| Description | The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008] |
|---|---|
| SKU | Y021035 |
| Unit quantity | 100 μg |
| Clone | N/A |
| Raised in | Rabbit |
| Clonality | Polyclonal |
| Species Reactivity | Human, Mouse, Rat |
| Specificity | Myc (Ab-358) antibody detects endogenous levels of total Myc protein. |
| Immunogen | The antiserum was produced against synthesized non-phosphopeptide derived from human Myc around the phosphorylation site of threonine 358 (R-R-TP-H-N). |
| Applications | WB: 1:500~1:1000 IHC: 1:50~1:100 |
| Recommended Dilutions | WB: 1:500~1:1000 IHC: 1:50~1:100 |
| Formulation | Liquid |
| Concentration | 1ug/ul |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Storage Buffer | phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Guarantee | abm guarantees that all our Anti-Myc (Ab-358) Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Purity | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
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