|G028||2000 U (1.0 ml)|
DNase I is a non-specific endonuclease derived from bovine pancreas that catalyzes the cleavage of phosphodiester bonds in single/double-stranded DNA, chromatin, and RNA:DNA hybrids to generate di-and/or oligonucleotide (5’-phosphorylated and 3’-hydroxylated) end-products.
|Unit quantity||2000 U (1.0 ml)|
• Removes DNA from protein preparations
One unit is defined as the amount of DNase I that catalyzes the degradation of 1 μg of DNA in 10 minutes at 37 °C into tetranucleotides or smaller fragments.
|Can DNase I be used to degrade residual genomic DNA in purified RNA?|
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