FLAG-HnRNP-L Stable Expressing HEK293 Cell Line
|T6250||1x106 cells / 1.0 ml|
|Description||Actively transcribed genes are mediated by KMT3a in humans. Within that protein complex is a eukaryotic specific subunit heterogeneous nuclear ribonucleoprotein L (HnRNP-L). HnRNP-L is a member of a large family of RRM domain containing RNA-binding proteins. It has been implicated in various RNA-related processes particularly in mediating selective exon inclusion during alternative splicing and facilitating polyadenylation. This cell line can be used to study the role HnRNP-L plays in regulating chromatin modification as well as post transcriptional events and co-transcriptional pre-mRNA processing.|
|Species||Human (H. sapiens)|
|Applications||For Research Use Only|
|Cell Type||Drug Discovery Cell Lines|
|Expression Profile||Flag-tagged HnRNP-L|
|Preservation Protocol||1. Freeze Medium: Complete growth medium with 20% FBS and 10% DMSO.|
2. Storage Temperature: Liquid nitrogen vapour phase.
|Unit quantity||1x106 cells / 1.0 ml|
|QC||1) MALDITOF/TOF; 2) RNase treatment and co-immunoprecipitation; 3) HKMT Assay; 4) RNAi knockdown of KMT3a and HnRNP-L; 5) Immunofluorescence|
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