iPSC Reprogramming

One of the major goals of iPSC research is for disease modeling and novel therapeutic (clinical) applications. To simplify iPSC induction, scientists at abm have successfully developed a broad line of iPSC reprogramming factors including proteins, lysates, lentiviruses, adenoviruses, minicircle DNA and cord blood episomal iPSC vectors.

Scientists at abm Inc. provide researchers with the most comprehensive reprogramming vectors for iPSC research. Every vector has been sequenced and rigorously tested to ensure functionality. With those tools readily available, research scientists can now focus on their research projects without having to spend time on the development of basic vectors of their own. Preliminary customer feedback has shown that the episomal plasmids we designed and lentivirus we produced are also significantly more efficient in reprogramming fibroblasts from mice, rats and humans than other similar vectors on the market.


Key Features

  • Human and mouse recombinant iPSC proteins in either crude cell lysate or purified protein format completely eliminates genome manipulation associated with vector-based iPSC factors.
  • Comprehensive selection of iPSC lentiviral vectors and viruses with choice of different promoters, plus a polycistronic iPSC lentivector or lentivirus containing all four transcription factors in the Thomson (OSNL) Protocol.
  • Adenovirus formats for highly efficient, non-integrating transient transduction in most cell lines, based on human adenovirus type 5 and prepared in high titer format for immediate applications.
  • Minicircle DNA, available with either a CMV or EF1α promoter and a GFP reporter for transgene expression, is the only truly xeno-free plasmid without any sequence of bacterial or viral origin and is ideal for xeno-free iPSC reprogramming.
  • Using oriP/EBNA1 (Epstein-Barr nuclear antigen-1)-based episomal vectors have been shown to be effective in the reprogramming of human cord blood cells (CB) or peripheral blood (PB) cells, presenting great potential applications in future regenerative medicine due to its easy accessibility as compared to isolation of same type of cells from bone marrow.
  • Licensed from the University of Toronto, highly sensitive and universally applicable EOS lentiviral and adenoviral vectors are available for immediate iPSC identification. The EOS (Early Transposon promoter and Oct-4 and Sox2 enhancers) element is a newly identified promoter that is only functional in stem cells, not differentiated cells, and is thus useful as a reporter promoter for stem cell identification.

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  1. Price: $950.00
    Unit: 200 μl


  2. Price: $1,250.00
    Unit: 200 μl
    The 3rd generation polycistronic lentivirus expresses all of the four human transcription factors (hOSNL of Thomson set: Oct4, Sox2, Lin28 and Nanog) within a single expression cassette under the control of EF1α promoter. Each of the factor's ORF...


  3. Price: $775.00
    Unit: 5 x 200 μl
    Five Lenti-III-EF1α viruses, expressing the Thomson iPSC factor set (mOct4, mSox2, mNanog and mLin28) and a GFP control. Purified ready-to-use high titer lentivirus at 1x107 cfu/mL


  4. Price: $1,600.00
    Unit: 200 μl
    The polycistronic lentivirus expresses all of the four mouse transcription factors (mOSNL of Thomson set: mOct4, mSox2, mNanog or mLin28) within a single expression cassette under the control of EF1α promoter. Each of the factor's ORF is separated...


  5. Price: $775.00
    Unit: 5 x 200 μl
    Five Lenti-III-EF1α viruses, expressing the Thomson iPSC factor set (Oct4, Sox2, Nanog and Lin28) and a GFP control. Purified ready-to-use high titer lentivirus at 1x107 cfu/mL


  6. Price: $1,700.00
    Unit: 5 x 200 μl
    Five Lenti-III-UbC viruses, expressing the Thomson iPSC factor set (Oct4, Sox2, Nanog and Lin28) and a GFP control. Purified ready-to-use high titer lentivirus at 1x107 cfu/mL


  7. Price: $1,700.00
    Unit: 5 x 200 μl
    Five Lenti-III-PGK viruses, expressing the Thomson iPSC factor set (Oct4, Sox2, Nanog and Lin28) and a GFP control. Purified ready-to-use high titer lentivirus at 1x107 cfu/mL


  8. Price: $750.00
    Unit: 5 x 200 μl
    Five Lenti-III-CMV viruses, expressing the Thomson iPSC factor set (Oct4, Sox2, Nanog and Lin28) and a GFP control. Purified ready-to-use high titer lentivirus at 1x107 cfu/mL


  9. Price: $1,600.00
    Unit: 200 μl
    The polycistronic lentivirus expresses all of the four human transcription factors (hOSNL of Thomson set: Oct4, Sox2, Nanog or Lin28) within a single expression cassette under the control of EF1α promoter. Each of the factor's ORF is separated by a...

9 Items

per page
Set Descending Direction