RNAi Technology

For gene regulation and functional studies, abm offers a variety of expression systems for:

  1. siRNA: efficiently express any target siRNA to knockdown any gene without the need to design hair-pin loop shRNA structures, available in lentivirus, AAV and Adenovirus.
  2. miRNA: inhibit or over-express any miRNA for studies of post-transcriptional gene regulation in mammalian systems using our ready-to-use viral vectors and packaged viruses, as well as our detection and quantification tools.
  3. UTR Reporters: quantitatively study a specific miRNA's regulation of its target gene using our 3’UTR or 5’UTR platform, all available as a library of premade lentiviral vectors and lentiviruses for any human, mouse or rat gene.
"The lentivirus (Cat. No. iV059988a) I received is working really well with my primary bone marrow stem cells. The transfection rate is nearly 70% in five days. Great product, I would like to continue to using your products."

Wei Guo, University of Maryland, Ccl4 siRNA Lentivirus (Rat), Cat. No. iV059988a

Services

Search Library

RNAi Technology Library

We offer genome-wide libraries of siRNA and miRNA overexpression, inhibitors, UTR reporters, and qPCR primers for human, mouse, and rat in a full complement of viral and non-viral delivery systems.

Resources

  • Introduction to miRNA
    Introduction to miRNA
    miRNA Knowledge Base
  • miRNA Detection
    miRNA Detection
    miRNA Knowledge Base
  • miRNA Target Prediction and Functional Analysis
    miRNA Target Prediction and Functional Analysis
    miRNA Knowledge Base
  • Viral Expression Systems Brochure
    Viral Expression Systems Brochure
    Introductory Guide

Top Publications

01

Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection

Gobbetti, T. et al.
PNAS (2017)


doi: 10.1073/pnas.1617290114

02

Transcriptional and posttranscriptional regulation of HOXA13 by lncRNA HOTTIP facilitates tumorigenesis and metastasis in esophageal squamous carcinoma cells

Lin, C. et al.
Oncogene (2017)


doi: 10.1038/onc.2017.133

03

MicroRNA-218 functions as a tumor suppressor in lung cancer by targeting IL-6/STAT3 and negatively correlates with poor prognosis

Yang, Y. et al.
Mol Cancer (2017)


doi: 10.1186/s12943-017-0710-z

Testimonials

ABM offers an excellent miRNA specific cDNA conversion kit for cheaper than other life science suppliers. The shipped my order quickly and it arrived earlier than expected. I will continue to use ABM for my other research needs.

Christian Andersen
The University of Georgia

miRNA cDNA Synthesis Kit with Poly(A) Polymerase Tailing, Cat. G902)

The lentivirus (Cat. No. iV059988a) I received is working really well with my primary bone marrow stem cells. The transfection rate is nearly 70% in five days. Great product, I would like to continue to using your products.

Wei Guo
University of Maryland

Ccl4 siRNA Lentivirus (Rat), Cat. iV059988a

I ordered products from ABM twice and the end user in our Lab was very happy with the quality of the products and fast delivery method as well.

Nadia Jordan-Spasov
Yale University

miRNA Primers and miRNA cDNA Synthesis Kit, Cat. G269

Promotions

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  1. Price: $125.00~$695.00
    microRNAs (miRNAs) are small non-coding RNA sequences important for gene regulation. This let-7a-2-3p miRNA can be used in experiments to investigate post-translational gene regulation by mimicking the effect of the endogenous miRNA.


  2. Sku: mm6941
    Price: $245.00
    Unit: 1.0 ml
    This miRNA inhibitor adenovirus is part of abm’s Adenoviral Expression System and can be used directly to transiently inhibit your miRNA of interest in a wide range of host cells. This adenovirus can be used to amplify more adenovirus by...


  3. Sku: mm31941
    Price: $215.00
    Unit: 500 ng
    This miRNA inhibitor lentiviral vector is part of abm’s Lentivirus Expression System and can be packaged into virus using an appropriate packaging mix to inhibit your miRNA of interest in a wide range of host cells or animal models. This...


  4. Sku: mm36941
    Price: $485.00
    Unit: 2 x 50 μl
    This ready-to-use miRNA inhibitor lentivirus is part of abm’s Lentivirus Expression System and can be used directly to inhibit your miRNA of interest in a wide range of host cells or animal models. This virus contains a GFP reporter for...


  5. Sku: mr5766
    Price: $245.00
    Unit: 1.0 ml
    This miRNA inhibitor adenovirus is part of abm’s Adenoviral Expression System and can be used directly to transiently inhibit your miRNA of interest in a wide range of host cells. This adenovirus can be used to amplify more adenovirus by...


  6. Sku: mr35766
    Price: $485.00
    Unit: 2 x 50 μl
    This ready-to-use miRNA inhibitor lentivirus is part of abm’s Lentivirus Expression System and can be used directly to inhibit your miRNA of interest in a wide range of host cells or animal models. This virus contains a GFP reporter for...


  7. Sku: mr30766
    Price: $215.00
    Unit: 500 ng
    This miRNA inhibitor lentiviral vector is part of abm’s Lentivirus Expression System and can be packaged into virus using an appropriate packaging mix to inhibit your miRNA of interest in a wide range of host cells or animal models. This...


  8. Sku: mr5765
    Price: $245.00
    Unit: 1.0 ml
    This miRNA inhibitor adenovirus is part of abm’s Adenoviral Expression System and can be used directly to transiently inhibit your miRNA of interest in a wide range of host cells. This adenovirus can be used to amplify more adenovirus by...


  9. Sku: mr35765
    Price: $485.00
    Unit: 2 x 50 μl
    This ready-to-use miRNA inhibitor lentivirus is part of abm’s Lentivirus Expression System and can be used directly to inhibit your miRNA of interest in a wide range of host cells or animal models. This virus contains a GFP reporter for...


  10. Sku: mr30765
    Price: $215.00
    Unit: 500 ng
    This miRNA inhibitor lentiviral vector is part of abm’s Lentivirus Expression System and can be packaged into virus using an appropriate packaging mix to inhibit your miRNA of interest in a wide range of host cells or animal models. This...

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