Recombinant Human 4-BBL (TNFSF9) (E. coli)
|Name||Recombinant Human 4-BBL (TNFSF9) (E. coli)|
|Description||Human 4-BBL or TNFSF9 is a member of the TNF superfamily. It is a type 2 transmembrane protein expressed on activated T-cells. It is a bidirectional signal transducer which acts as a costimulatory receptor molecule on T lymphocytes. Its functions primarily stimulate the immune response by promoting the release of cytokines such as IL-2 and IFN-gamma. TNFSF9 works with TNFRSF9 for the generation of cytotoxic T cells, proliferation of T-cells as well as antigen presentation. It also reactivates T lymphocytes which have become anergic. It is also expressed on activated NK cells, B-cells, macrophages, dendritic cells and some brain cells. Recombinant Human 4-BBL is a 19.6 kDa protein.|
|Organism||Human (H. sapiens)|
|Unit quantity||1.0 mg|
|Aliases||TNFSF9, CD137L, 4BBL|
|Species||Human (H. sapiens)|
|Molecular Weight||19.6 kDa|
|Endotoxin Level||<1.0 EU/µg of recombinant protein as determined by the LAL method.|
|Purity||>95% as determined by SDS-PAGE|
|Formulation||Lyophilized from a 0.2 µm filtered solution in PBS, pH 7.4|
|Reconstitution||A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.|
|Storage||The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.|
|Usage||For research use only. Not for diagnostic or therapeutic use.|
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