Recombinant Human AKT2 (N-GST tag)

CAT.NOUNITPRICE
Z50000510 µg
$325.00

Specifications


DescriptionAKT2 or Protein Kinase B ß (PKBß) is a serine/threonine kinase that is a member of the AKT family. AKT2 like the other AKT members is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix components and is involved in glucose metabolism, transcription, survival, cell proliferation, angiogenesis, and cell motility. The PI3K generates phosphatidylinositol-3,4,5-trisphosphate (PIP3), a lipid second messenger essential for the translocation of AKT2 to the plasma membrane where it is phosphorylated and activated by phosphoinositide-dependent kinase-1 (PDK-1).
SKUZ500005
Accession NumberNM_001626
AppearanceLiquid
AliasesPRKBB; PKBBETA; RAC-BETA
Formulation50mM Tris-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Gene SymbolAKT2/PKB beta
SourceInsect cells
Molecular Weight85.0 kDa
SpeciesHuman (H. sapiens)
UsageFor research use only. Not for diagnostic or therapeutic use.
StorageStore product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Unit quantity10 µg
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