Recombinant Human FGF4 (E. coli)
Cat. No. | Z102605 |
Name | Recombinant Human FGF4 (E. coli) |
Description | A member of the FGF family, FGF4 plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiation. FGF4 binds to anionic glycosaminoglycans heparin and heparin sulfate with high affinity and mediates its diverse functions through the FGF receptors (FGFR) 1c, 2c, 3c, and 4. Human FGF4 is known to exhibit cross species activity with mouse, rat, bovine and canine FGF4. Recombinant Human FGF4 is a single polypeptide of 20 kDa. |
Organism | Human (H. sapiens) |
Unit quantity | 25 µg |
Family | FGF Family |
Aliases | Heparin-binding growth factor 4, HBGF-4, Heparin secretory-transforming protein 1, HST, HST-1, HSTF-1, Transforming protein KS3, FGFK, KFGF, Kaposi’s sarcoma associated FGF |
Gene Symbol | FGF4 |
Gene ID | 2249 |
Accession Number | P08620 |
Source | E. coli |
Species | Human (H. sapiens) |
Appearance | Lyophilized Powder |
Molecular Weight | 20 kDa |
Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method |
Purity | >95% as determined by SDS-PAGE |
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS (pH 8.0) |
Function | The ED50 as determined by the dose-dependent stimulation of mouse fibroblasts was <0.2 ng/ml |
Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
Usage | For research use only. Not for diagnostic or therapeutic use. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z102605 |
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