Recombinant Mouse IL7

Cat. No.
Z200645
Unit
10 µg
Price
$205.00
Cat. No. Z200645
Name Recombinant Mouse IL7
Description IL7 is a hematopoietic growth factor constitutively produced by stromal cells from the bone marrow and thymus. It is critical for B and T cell development and survival. IL7 promotes the differentiation of hematopoietic stem cells to lymphoid precursor cells by binding to a receptor composed of common gamma chain and IL-7Ra (CD127). Lymphoid precursor cells give rise to T cells, B cells, and natural killer cells. Furthermore, IL7 provides signals to regulate the survival of naive and memory CD4+ and CD8+ T cells NK T cells, innate lymphoid cells, and T regulatory cells. During B-cell development, IL7 also provides signals to promote survival, proliferation and differentiation. Recombinant mouse IL7 is a non-glycosylated protein with a molecular mass of 15.2 kDa.
Organism Mouse (M. musculus)
Unit quantity 10 µg
Family Other Interleukins
Aliases Interleukin-7
Gene Symbol IL7
Gene ID 16196
Source E. coli
Species Mouse (M. musculus)
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 µm filtered solution in PBS and 2% trehalose, pH 7.4
Reconstitution A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage This protein can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z200645
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