Lung Health Cell Collection

Advancing Lung Research Through Better Models

Translationally Relevant Respiratory Cell Models for Lung Health Research

80+ lung and airway cell models for cancer biology, infectious disease, pulmonary disorders, and functional genomics

This May, in recognition of Lung Health Awareness Month and World Asthma Day, we highlight the importance of advancing respiratory research through reliable model systems.

At abm, we offer a comprehensive portfolio of lung and airway cell models designed to support research across cancer biology, infectious disease, and pulmonary disorders. From lung cancer cell lines and airway epithelial cells to engineered and CRISPR-based systems, these models enable reproducible and scalable experimental workflows.

80+Cell Models
4Core Model Types
Human + AnimalSpecies Coverage
Engineered SystemsFunctional Analysis
Lung + AirwayTissue Relevance


Key Features for Lung Health Research

Our collection is built to support respiratory research workflows spanning oncology, airway biology, infectious disease, functional genomics, disease modelling, and translational studies.

Respiratory Oncology
Diverse lung cancer models

A broad range of lung tumour cell lines supports drug discovery, target validation, mutation-driven studies, and oncology screening workflows.

Airway Biology
Airway and epithelial systems

Lung, bronchial, alveolar, and small airway models help researchers investigate epithelial function, barrier biology, COPD, cystic fibrosis, and airway disease mechanisms.

Engineered Systems
Stable and CRISPR-based models

CRISPR knockout, stable expression, reporter, and knockdown systems enable functional genomics, host response analysis, pathway discovery, and imaging-based readouts.

Translational Breadth
Human and animal model coverage

Models from human, mouse, bovine, canine, porcine, and other species support translational respiratory research and comparative biology.

Research Applications and Full Collection

Explore our full range of respiratory-derived models below. Browse by application area or view the complete lung and airway cell model collection.

Cat. No. Product Name Species Tissue Donor
T3484 IFNαR2 Stable Knockout AK-D 2.2 Cell Line Cat (Feline) Lung
T3422 CHCHD5 CRISPR Knockout A549 Cell Line - T1-U23 Human (H. sapiens) Lung
T3416 EZH2 CRISPR Knockout A549 Cell Line - M31 Human (H. sapiens) Lung Male, 58, White, Lung cancer
T9505 FRK Stable Knockout Human H1299 Cell Line Human (H. sapiens) Lung Male, Caucasian, 43, Lymph node metastasis of the lung
T6603 GBA CRISPR Knockout A549 Stable Cell Line Human (H. sapiens) Lung Male, 58 , Caucasian, Carcinoma
T6199 GFAT1 CRISPR Stable Knockout H1299 Cell Line Human (H. sapiens) Lung Male, Caucasian, 43, Lymph node metastasis of the lung
T3517 Human IFNAR1 CRISPR Knockout A549 Stable Cell Line Human (H. sapiens) Lung Male, 58, White, lung cancer
T3519 Human IFNAR1-IFNLR1 CRISPR Knockout A549 Stable Cell Line Human (H. sapiens) Lung Male, 58, White, lung cancer
T3518 Human IFNLR1 CRISPR Knockout A549 Stable Cell Line Human (H. sapiens) Lung Male, 58, White, lung cancer
T6564 IRF3 CRISPR Knockout A549 Stable Cell Line Human (H. sapiens) Lung Male, 58, White, Lung cancer
T3415 IRF9 CRISPR Knockout A549 Cell Line - T2 AA201 Human (H. sapiens) Lung Male, 58, White, Lung cancer
T6565 MAVS CRISPR Knockout A549 Stable Cell Line Human (H. sapiens) Lung Male, 58, White, Lung cancer
T7360 MAVS CRISPR Knockout A549 Stable cell line-T2-7 Human (H. sapiens) Lung
T9510 NLK CRISPR Knockout Human A549 Stable Cell Line Human (H. sapiens) Lung Male, 58, Caucasian, Lung carcinoma
T6827 PTPRA CRISPR Knockout Immortalized Human Lung Fibroblast Cell Line Human (H. sapiens) Lung
T6575 RNF213 CRISPR Knockout A549 Stable Cell Line - Clone 2 Human (H. sapiens) Lung Male, 58 years old, Caucasian, Lung adenocarcinoma
T6543 SCYL1 CRISPR Knockout A549 Stable Cell Line - Clone 3E1 Human (H. sapiens) Lung Male, 58, White, Lung cancer
T6562 STAT1 CRISPR Knockout A549 Stable Cell Line Human (H. sapiens) Lung Male, 58, White, Lung cancer
T6563 STAT2 CRISPR Knockout A549 Stable Cell Line Human (H. sapiens) Lung
T3829 TRPV6 CRISPR Knockout A549 Cell Line - AN306 Human (H. sapiens) Lung Male, 58, White, Lung cancer
T3806 UBE2M-/+ CRISPR Knockout A549 Stable Cell Line Human (H. sapiens) Lung Male, 58, White, Lung cancer
T3492 Ext1 Stable Knockout Heparan Sulfate Cell Line (Ext1-/-) Mouse (M. musculus) Lung Adult C57BL6
T3491 Ext1 Wild-Type Heparan Sulfate Stable Cell Line (Ext1f/f) Mouse (M. musculus) Lung Adult C57BL6
T3376 Glce Stable Knockout Heparan Sulfate Cell Line (Glce-/-) Mouse (M. musculus) Lung Adult C57BL6
T3383 Hs3st1 Stable Knockout Heparan Sulfate Cell Line (Hs3st1-/-) Mouse (M. musculus) Lung Adult C57BL6
T3385 Hs3st1;Hsst4 Stable Knockout Heparan Sulfate Cell Line (Hs3st1-/-;Hsst4-/-) Mouse (M. musculus) Lung Adult C57BL6
T3384 Hs3st4 Stable Knockout Heparan Sulfate Cell Line (Hs3st4-/-) Mouse (M. musculus) Lung Adult C57BL6
T3382 Hs6st1;Hs6st2 Stable Knockout Heparan Sulfate Cell Line (Hs6st1-/-;Hs6st2-/-) Mouse (M. musculus) Lung Adult C57BL6
T3381 Hs6st1f/f;Hs6st2-/- Heparan Sulfate Stable Cell Line (Hs6st1f/f;Hs6st2-/-) Mouse (M. musculus) Lung Adult C57BL6
T3374 Ndst1 Stable Knockout Heparan Sulfate Cell Line (Ndst1-/-) Mouse (M. musculus) Lung Adult C57BL6
T3490 Ndst1/Ndst2 Stable Knockout Heparan Sulfate Cell Line (Ndst1-/- ;Ndst2-/-) Mouse (M. musculus) Lung Adult C57BL6
T3375 Ndst1f/f ;Ndst2-/- Heparan Sulfate Stable Cell Line (Ndst1f/f ;Ndst2-/-) Mouse (M. musculus) Lung Adult C57BL6
T3387 Sulf1/Sulf2 Stable Knockout Heparan Sulfate Cell Line (Sulf1-/-;Sulf2-/-) Mouse (M. musculus) Lung Adult C57BL6
T0831 Immortalized Bovine Lung Microvascular Endothelial Cells (BLuMEC) Cow (Bovine) Lung
T0091 Immortalized Fetal Bovine Lung Cells - SV40 Cow (Bovine) Lung
T0892 Immortalized Canine Alveolar Epithelial Cells - SV40 Dog (Canine) Lung Not disclosed
T0838 Immortalized Canine Lung Microvascular Endothelial Cells (CLuMEC) Dog (Canine) Lung
T0095 Immortalized Equine Lung Cells (extEqFL) Horse (Equine) Lung 5-month old, equine fetus
T0406 Immortalized COPD Bronchial/Trachael Epithelial Cells - SV40T Human (H. sapiens) Lung Not disclosed
T0753 Immortalized Human Bronchial Epithelial Cells (HBEC3-KT) - Cdk4/hTERT Human (H. sapiens) Airway Not disclosed
T0497 Immortalized Human Bronchial Epithelial Cells - hTERT + CDK4 Human (H. sapiens) Airway Female, 55
T0498 Immortalized Human Bronchial Epithelial Cells - hTERT/BMI Human (H. sapiens) Airway Female, 55
T0486 Immortalized Human Bronchial Epithelial Cells - SV40 Human (H. sapiens) Airway Female, 55
T0493 Immortalized Human Bronchial Smooth Muscle Cells Human (H. sapiens) Airway Male, 27, Caucasian
T0738 Immortalized Human Delta F508 Cystic Fibrosis Cells Human (H. sapiens) Airway Female, 54, Delta F508 Cystic Fibrosis
T1013 Immortalized Human Diploid Fibroblasts - hTERT Human (H. sapiens) Lung Female, 3 months, Caucasian
T0850 Immortalized Human Laryngeal Epithelial Cells (HuLa-TVC) Human (H. sapiens) Airway Female, 32
T0795 Immortalized Human Lung Epithelial Cells (BEAS-2B-BW 1799) Human (H. sapiens) Lung Healthy donor
T0797 Immortalized Human Lung Epithelial Cells (BEAS-2B-CSC 1170-I) Human (H. sapiens) Lung Healthy donor
T0794 Immortalized Human Lung Epithelial Cells (BEAS-2B-CSC 1196) Human (H. sapiens) Lung Healthy donor
T0796 Immortalized Human Lung Epithelial Cells (BEAS-2B-CSC 1198) Human (H. sapiens) Lung Healthy donor
T1015 Immortalized Human Lung Fibroblast - hTERT Human (H. sapiens) Lung Female, 16 weeks, Caucasian
T0881 Immortalized Human Lung Pericytes (Clone I3) - SV40 Human (H. sapiens) Lung Normal tissue
T0490 Immortalized Human Pulmonary Fibroblast Cells Human (H. sapiens) Lung Female, 65, Caucasian
T0399 Immortalized Human Small Airway Epithelial Cells (COPD) - SV40T Human (H. sapiens) Airway Not disclosed
T0485 Immortalized Human Small Airway Epithelial Cells - SV40 Human (H. sapiens) Airway Male, 46, Caucasian
T0206 Immortalized Human Type II Alveolar Epithelial Cells - SV40T+hTERT Human (H. sapiens) Lung Male
T0092 Immortalized Mouse Lung Clara Cells - Conditionally (C22) Mouse (M. musculus) Lung H-2Kb-tsA58 transgenic mouse
T0094 Immortalized Mouse Lung Endothelial Cells - PmT Mouse (M. musculus) Lung
T0754 Immortalized Porcine Alveolar Macrophage Cells (iPAM303) Pig (Porcine) Airway 10-week-old clinically healthy Yorkshire pigs
T0755 Immortalized Porcine Alveolar Macrophage Cells (iPAM61) Pig (Porcine) Airway 10-week-old clinically healthy Yorkshire pigs
T0741 Immortalized Porcine Alveolar Macrophage Cells (PAM-KNU) - hTERT Pig (Porcine) Airway 8 weeks old
T0391 Immortalized Porcine Fibroblast Cell Line (iKUF02) Pig (Porcine) Lung Landrace pig
T0394 Immortalized Porcine Fibroblast Cell Line (iKUF07) Pig (Porcine) Lung Landrace pig
T0883 Immortalized Rat Alveolar Epithelial Cells - SV40 Rat (R. norvegicus) Lung
T9207 Immortalized Rat Pulmonary Microvascular Endothelial Cells - SV40 Rat (R. norvegicus) Lung
T0733 Immortalized Rat Tracheal Epithelial Cells (SPOC-1) Rat (R. norvegicus) Airway 10 - 14 weeks old
T3030 Nav2.1/β1/Contactin Stable Chinese Hamster Lung Cell Line Chinese Hamster (C. griseus) Lung
T3235 A549 Cells Stably Expressing hACE2 Receptor and TMPRSS2 (A549-AT) Human (H. sapiens) Lung Male, 58, Caucasian, Lung carcinoma
T3253 Cas9 Expressing A549 Cell Line Human (H. sapiens) Lung Male, 58, Caucasian, Lung carcinoma
T7724 Cas9 Expressing PC-9 Stable Cell Line Human (H. sapiens) Lung
T9823 Cdc42(Human) Stable Overexpression A549 Cell Line - Clone #34 Human (H. sapiens) Lung Male, 58, White, Lung cancer
T6213 DDP Resistant A549 Cell Line Human (H. sapiens) Lung Male, 58, Caucasian, Lung carcinoma
T9645 EEF1A1 Stable Overexpressing A549 Cell Line - Clone #22 Human (H. sapiens) Lung Male, 58, Caucasian, Lung carcinoma
T8238 EGFP/G418 Resistant H1299 Cells Human (H. sapiens) Lung Male, Caucasian, 43, Lymph node metastasis of the lung
T6843 EMT Dual Reporter A549 Cell Line Human (H. sapiens) Lung Male, 58, Caucasian, Lung adenocarcinoma
T6262 Fat-1 Stable A549 Cell Line Human (H. sapiens) Lung Male, 58, Caucasian, Lung carcinoma
T6263 Fat-1 Stable PC9 Cell Line Human (H. sapiens) Lung Male, 45, Lung adenocarcinoma
T6464 FGFR1 Stable HCC827 Cell Line Human (H. sapiens) Lung Female, 39, Caucasian, Adenocarcinoma
T6465 FGFR1 Stable PC9 Cell Line Human (H. sapiens) Lung Male, 45, Lung adenocarcinoma
T3919 GFP Stably Expressing A549 Cell Line Human (H. sapiens) Lung Male, 58, Caucasian, Lung carcinoma
T6171 GFP1-10 Stable Expressing A549 Cell Line Human (H. sapiens) Lung Male, 58, Caucasian, Lung carcinoma
T6415 hTR and hTERT Stable Expressing H1299 Cell Line Human (H. sapiens) Lung Male, Caucasian, 43, Lymph node metastasis of the lung
T6197 K-Ras G12C Stable AALE Cell Line Human (H. sapiens) Lung
T3311 LKB1 Stable Knockdown Cell Line (H1299-408) Human (H. sapiens) Lung Male, Caucasian, 43, Lymph node metastasis of the lung
T3312 LKB1 Stable Knockdown Cell Line (H1650-408) Human (H. sapiens) Lung Male, Caucasian, 43, Lymph node metastasis of the lung
T3313 LKB1 Stable Knockdown Cell Line (H522-408) Human (H. sapiens) Lung Male, Caucasian, 43, Lymph node metastasis of the lung
T9610 Scrambled (spCas9) Negative Control H1299 Cell Line Human (H. sapiens) Lung Male, Caucasian, 43, Lymph node metastasis of the lung
T6165 SIRT7 Stable Knockdown H1299 Cell Line Human (H. sapiens) Lung Male, Caucasian, 43, Lymph node metastasis of the lung
T6259 SIRT7 Stable Scramble H1299 Cell Line Human (H. sapiens) Lung Male, Caucasian, 43, Lymph node metastasis of the lung
T6325 Stable Rab37 Knockdown H460 Lung Cancer Cell Line (shRab37#1) Human (H. sapiens) Lung Male, Carcinoma
T6326 Stable Rab37 Knockdown H460 Lung Cancer Cell Line (shRab37#2) Human (H. sapiens) Lung Male, Carcinoma
T7726 Cas9 Expressing B16-F10 Stable Cell Line Mouse (M. musculus) Lung
T6305 Cytochrome c Stable Knockout Mouse Fibroblast Cell Line Mouse (M. musculus) Lung
T3378 Hs2st1 Stable Knockout Heparan Sulfate Cell Line (Hs2st1-/-) Mouse (M. musculus) Lung Adult C57BL6
T3377 Hs2st1 Wild-Type Heparan Sulfate Stable Cell Line (Hs2st1f/f) Mouse (M. musculus) Lung Adult C57BL6
T3380 Hs6st1 Stable Knockout Heparan Sulfate Cell Line (Hs6st1-/-) Mouse (M. musculus) Lung Adult C57BL6
T3379 Hs6st1 Wild-Type Heparan Sulfate Stable Cell Line (Hs6st1f/f) Mouse (M. musculus) Lung
T3343 Murine EML4-ALK Expressing Stable Cell Line (EA1) Mouse (M. musculus) Lung
T3344 Murine EML4-ALK Expressing Stable Cell Line (EA3) Mouse (M. musculus) Lung
T3373 Ndst1 Wild-Type Heparan Sulfate Stable Cell Line (Ndst1f/f) Mouse (M. musculus) Lung Adult C57BL6
T6304 Rieske ISP Stable Knockout Mouse Fibroblast Cell Line Mouse (M. musculus) Lung
T3386 Sulf1/Sulf2 Wild-Type Heparan Sulfate Stable Cell Line (Sulf1f/f;Sulf2f/f) Mouse (M. musculus) Lung Adult C57BL6
T1077 A549 Cells Human (H. sapiens) Lung Male, 58 , Caucasian, Carcinoma
T9180 BEAS-2B Cells Human (H. sapiens) Lung Normal, Bronchus
T8420 Calu-1 Cells Human (H. sapiens) Lung Male, 47, Caucasian, Squamous cell lung carcinoma
T8421 Calu-3 Cells Human (H. sapiens) Lung Male, 25, Caucasian, Lung adenocarcinoma
T9172 HCC827 cells Human (H. sapiens) Lung 39, Female. White, Adenocarcinoma
T8135 LUJ-35T Cell Line Human (H. sapiens) Lung Lung Carcinoma
T7003 MRC-5 Cells Human (H. sapiens) Lung Male, 14 weeks gestation (fetus), Normal lung tissue
T1214 NCI-H1688 Cells Human (H. sapiens) Lung Male, Caucasian, Carcinoma
T1230 NCI-H23 Cells Human (H. sapiens) Lung Male, 51, Black, Adenocarcinoma
T9902 NCI-H460 Cells Human (H. sapiens) Lung Male, Lung carcinoma
T9028 NCl-H1975 Cells Human (H. sapiens) Lung Adenocarcinoma
T8422 SK-LU-1 Cells Human (H. sapiens) Lung Female, 60, White, Lung adenocarcinom
T8423 SK-MES-1 Cells Human (H. sapiens) Lung Male, 65, Caucasian, lung squamous cell carcinoma
T8146 Distant Pulmonary Metastasis Tumor Cell Line (T3-PA) Mouse (M. musculus) Lung Obtained by intravenous injection of parent cell line (T2-A) in the tail vein of nude NIH Swiss mice and selection of cells from a lung metastasis.
T8024 E889 Cells Mouse (M. musculus) Lung Male, C57BL/6, Krasᴳ¹²ᴰ Map3K7ᶠˡ/ᶠˡ ROSAᵐᵀᵐᴳ
T8148 Highly Metastatic Distant Pulmonary Tumor Cell Line (T4-PA) Mouse (M. musculus) Lung Highly metastatic. Produces widespread metastatic lesions throughout the bodies of nude NIH Swiss mice when injected intravenously. Obtained by injection of parent cell line (T3-HA) in the tail vein of nude NIH Swiss mice and selection of cells from a lun
T1016 LLC Cells Mouse (M. musculus) Lung C57BL/6, Lewis lung carcinoma
T8090 Lung Squamous Cell Carcinoma Cell Line (UN-SCC679) Mouse (M. musculus) Lung Female A/J strain lung
T8091 Lung Squamous Cell Carcinoma Cell Line (UN-SCC680) Mouse (M. musculus) Lung Female A/J strain lung
T8096 Murine KRAS(G12C) Lung Tumor Cell Line (mKRC.1) Mouse (M. musculus) Lung
T8097 Murine KRAS(G12C) Lung Tumor Cell Line (mKRC.2) Mouse (M. musculus) Lung
T8025 X381 Cells Mouse (M. musculus) Lung Male, C57BL/6, Krasᴳ¹²ᴰ Pten ᶠˡ/⁺ p53ᶠˡ/⁺ ROSAᵐᵀᵐᴳ
T8022 X577 Cells Mouse (M. musculus) Lung Male, C57BL/6, Krasᴳ¹²ᴰ Smad4ᶠˡ/⁺
T8023 X911 Cells Mouse (M. musculus) Lung Male, C57BL/6, Krasᴳ¹²ᴰ Tgfbr2ᶠˡ/ᶠˡ
T8027 Y143 Cells Mouse (M. musculus) Lung Female, C57BL/6
T8026 Y856 Cells Mouse (M. musculus) Lung Female, C57BL/6, R26Stopᶠᴸ P110*ᶠˡ/⁺ p53ᶠˡ/⁺
T9909 OAR-L1 Cells Sheep (Ovine) Lung Female

Additional Research Support

In further support of lung health researchers, abm also provides gene tools and cell engineering services to help advance pathway discovery, model development, respiratory disease studies, and screening workflows.

The abm Difference

More than a supplier, abm is your research partner — delivering trusted quality, rapid access, and expert support from project start to publication.

Ship-Ready Inventory

Our in-stock collection is prepared for fast fulfilment, helping you reduce downtime and move from planning to benchwork without unnecessary delays.

Scientist-to-Scientist Support

Our PhD-level team works with you directly to help identify the right model, recommend culture conditions, and support more complex study design questions.

Complete Documentation

Each order includes essential documentation such as CoA, passage history, culture guidance, and mycoplasma test reports for streamlined lab integration.

Trusted by Thousands

abm cell lines support work across oncology, pharmacology, respiratory biology, and molecular biology, helping researchers generate reliable data backed by trusted materials.

Explore abm’s Lung and Airway Cell Models

Browse the collection, request a quote, or contact our team for more information.