Mast Cell Research Collection

Characterized Mast Cell Lines and Reagents for Reliable In Vitro Studies

7 mast cell lines and 17 supporting reagents for histamine release and degranulation assays

Mast cells are key mediators of allergic and inflammatory responses. Located at tissue interfaces such as the skin, airways, and gastrointestinal tract, they respond to IgE–FcεRI activation and release histamine and other mediators that drive downstream effects.

abm offers human, mouse, and canine mast cell lines with supporting reagents for cell culture, cryopreservation, and histamine release assays, enabling consistent and efficient experimental workflows.

7Mast Cell Lines
17Supporting Materials
3Species


Key Features for Mast Cell Research

This collection supports mast cell biology, allergy research, and histamine release assays by combining relevant cell lines with matched supporting reagents in one place.

Functional Models

Mast cell lines with documented histamine release capability, alongside complementary models for mast cell biology, signalling, and assay development.

Cross-Species Coverage

Human, mouse, and canine cell lines to support translational and comparative studies in allergy and immunology.

Assay-Ready Support

Assay kits, antibodies, cytokines, media, and consumables selected to streamline experimental setup and downstream analysis.

Workflow Efficiency

Matched media, extracellular matrix, freezing media, and supplements to support reproducible workflows from thawing to assay execution.

Application Resource

Guidance for mast cell granulation assay setup, handling, and preparation to support consistent experimental performance.

Explore Mast Cell Research Tools

Browse mast cell lines and supporting reagents for histamine release assays, culture maintenance, cryopreservation, and workflow development.

Browse Mast Cell Lines

Filter the table by source to quickly narrow down the mast cell lines most relevant to your study design.

Use the filters below to refine the mast cell cell line list by source.

Cat. No. Product Name Species Source Histamine Release
T8157 Human Mast Cell Line (LAD2) Human Mast Cell Sarcoma/Leukemia Capable
T8156 Human Mast Cell Line (LADR) Human Bone Marrow Capable
T0843 Immortalized Human Mast Cells (LUVA) Human CD34+-enriched Mononuclear Cells Not Capable
T8389 HMC-1.3 Mast Cell Line (Clone 2E2) Human Mast Cell Leukemia Not Capable
T8388 HMC-1.3 Mast Cell Line (Clone 1H9) Human Mast Cell Leukemia Not Capable
T0788 Immortalized Mast Cells (NCL-2) Mouse NC Mouse Bone Marrow Capable
T8336 Canine Mastocytoma Cell Line (NI-1) Dog Mastocytoma Not Listed

Filter the supporting materials table by category to quickly find the reagents used with the mast cell lines.

Cat. No. Product Name Category Size Supports Cat. No.
Y70000 Human IgE Antibodies 10 μg T8157, T8156
Y79000 Anti-Human IgE Antibody Antibodies 10 μg T8157, T8156
G7800 Mast Granulation Assay Cell Assay Products 100 Tests T8157, T8156, T0843, T8389, T8388, T0788
TM078 CryoGuard™ Freezing Media Cell Freezing Device and Medium 50 ml T8157, T8156, T0843, T8389, T8388, T0788, T8336
TM024 Cryopreservation Medium Cell Freezing Device and Medium 100 ml T8389, T8388, T0788, T8336
G299 PriCoat™ T25 Flasks Culture Consumables 10 Flasks T0843, T8389, T8388, T0788, T8336
Z100815 Recombinant Human SCF (E. coli) Growth Factors and Cytokines 10 µg T8157, T8156
Z200445 Recombinant Mouse IL3 Growth Factors and Cytokines 10 µg T0788
TM8157 PriGrow X Series Medium for T8157 Media & Supplements 1 Kit T8157
G275 L-Glutamine Solution (200 mM) Media & Supplements 100 ml T8157, T8156, T0843, T8389, T8388
G255 Penicillin/Streptomycin Solution Media & Supplements 100 ml T8157, T8156, T0843, T8389, T8388, T0788, T8336
TM8156 PriGrow X Series Medium for T8156 Media & Supplements 1 Kit T8156
TM0843 PriGrow X Series Medium for T0843 Media & Supplements 1 Kit T0843
G422 Applied Cell Extracellular Matrix Media & Supplements 25 ml T8389, T8388, T0788
TM505 Iscove’s Modified Dulbecco’s Medium (IMDM) Media & Supplements 500 ml T8389, T8388
TM018 PriGrow VIII Medium Media & Supplements 500 ml T0788
TM002 PriGrow II Medium Media & Supplements 500 ml T8336

The abm Difference

abm supports mast cell research with reliable products, efficient fulfilment, and practical technical guidance.

Ship-Ready Inventory

Mast cell lines and supporting materials maintained for efficient fulfilment to reduce delays between planning and execution.

Scientist-to-Scientist Support

PhD-level support to help select appropriate cell models, culture conditions, and reagents for histamine release and related assays.

Complete Documentation

Clear documentation to support onboarding, culture handling, and routine laboratory use.

Trusted Research Materials

Reproducible cell models and supporting reagents for reliable, well-controlled experimental workflows.

Advance Mast Cell Research with abm

Browse the mast cell collection, explore supporting reagents, or contact us for help selecting products for your workflow.