AAV siRNA Library
abm’s RNAi Expression System is now available in Adeno-Associated Virus format, combining the efficient expression of any siRNA with the advantage of non-integrating AAV for a new, powerful gene knockdown tool for gene therapy. The system is based on a unique convergent promoter design for greater efficiency of target gene knockdown without the need for a hair-pin loop structure commonly utilized in single promoter vectors, and includes a GFP reporter for monitoring transduction. abm offers a comprehensive library of human, mouse, and rat siRNAs in vector or pre-packaged AAV formats, available in multiple serotypes for tissue-specific knockdown.
Advantages of AAV siRNA:
- Uses more potent 27-29 bp oligos than the traditional 19 or 21 bp oligos.
- Convergent promoters to avoid hairpin loop structures, making sequencing and plasmid growth much easier.
- GFP reporter for monitoring transfection or viral infection.
- All constructs are available as a pooled set of 3 for improved gene knockdown.
- Use AAV for low immunogenicity and no integration into the host genome.
Search AAV siRNA Library
AAV siRNA Library
We offer siRNA AAV vectors and viruses for over 35000 human, mouse, and rat genes.
Can’t find the siRNA product you’re looking for? Request a custom siRNA construct with [email protected].
Product Information
-
Workflow
View our simplfied workflow with siRNA AAV vectors and viruses. -
Vector Map
pAAV-siRNA-GFP vector map. -
AAV Serotypes
We offer 9 AAV serotypes.
Documents
Top Publications
UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity.
Bi, X., et al.
eLife 7:e37993 (2018).
doi: 10.7554/eLife.37993.
Src-type tyrosine kinase p56lck is critical for thymic stromal lymphopoietin-induced allergic rhinitis.
Jeong, H.J., et al.
Clin Exp Allergy 48(7):875-889 (2018).
doi: 10.1111/cea.13167.
Carbon Monoxide Inhibits Islet Apoptosis via Induction of Autophagy.
Wang, H., et al.
Antioxid Redox Signal 28(14):1309-1322.
doi: 10.1089/ars.2016.6979.
Browse Products
-
Price: $85.00~$1,100.00This ZWS1 siRNA is available in lentivirus, AAV, and oligo formats. It can be used to knockdown the ZWS1 gene in a wide range of host cells via transduction or transfection.
-
Price: $85.00~$1,100.00This ZWINTAS siRNA is available in lentivirus, AAV, and oligo formats. It can be used to knockdown the ZWINTAS gene in a wide range of host cells via transduction or transfection.
-
Price: $85.00~$1,100.00This ZSCAN12L1 siRNA is available in lentivirus, AAV, and oligo formats. It can be used to knockdown the ZSCAN12L1 gene in a wide range of host cells via transduction or transfection.
-
Price: $85.00~$1,100.00This ZNF864P siRNA is available in lentivirus, AAV, and oligo formats. It can be used to knockdown the ZNF864P gene in a wide range of host cells via transduction or transfection.
-
Price: $85.00~$1,100.00This ZNF850P siRNA is available in lentivirus, AAV, and oligo formats. It can be used to knockdown the ZNF850P gene in a wide range of host cells via transduction or transfection.
-
Price: $85.00~$1,100.00This ZNF838 siRNA is available in lentivirus, AAV, and oligo formats. It can be used to knockdown the ZNF838 gene in a wide range of host cells via transduction or transfection.
-
Price: $85.00~$1,100.00This ZNF834 siRNA is available in lentivirus, AAV, and oligo formats. It can be used to knockdown the ZNF834 gene in a wide range of host cells via transduction or transfection.
-
Price: $85.00~$1,100.00This ZNF833 siRNA is available in lentivirus, AAV, and oligo formats. It can be used to knockdown the ZNF833 gene in a wide range of host cells via transduction or transfection.
-
Price: $85.00~$1,100.00This ZNF828 siRNA is available in lentivirus, AAV, and oligo formats. It can be used to knockdown the ZNF828 gene in a wide range of host cells via transduction or transfection.
-
Price: $85.00~$1,100.00This ZNF826 siRNA is available in lentivirus, AAV, and oligo formats. It can be used to knockdown the ZNF826 gene in a wide range of host cells via transduction or transfection.