Custom Peptide Synthesis Service

abm is a leading company in custom peptide synthesis. Through innovation, abm has developed a variety of proprietary technologies that allow us to provide the highest quality custom synthetic peptides at the most competitive prices.

Contact us today for your custom peptide order!




"I am a fan of abm: great product quality, great price, great rewards and great experience."

Dr. Vincent Emond, Centre de recherche du CHU de Québec CHUL

Service Details

Purity
AmountCrudeDesalted>75%>80%>85%>90%>95%>98%
1‑4 mg $3.31 $4.25 $7.13 $8.35 $9.50 $11.38 $12.17 $18.36
5‑9 mg $3.89 $4.97 $8.35 $9.72 $11.16 $13.32 $14.40 $21.60
10‑14 mg $4.61 $5.83 $9.79 $11.45 $13.10 $15.70 $16.92 $25.42
15‑19 mg $4.75 $5.98 $10.44 $13.46 $14.54 $17.35 $18.86 $28.37
20‑24 mg $5.11 $6.34 $12.38 $14.33 $16.27 $18.86 $21.46 $32.26
25‑29 mg $5.47 $6.70 $13.46 $15.41 $17.35 $19.94 $23.40 $34.99
30‑39 mg $5.76 $6.98 $14.54 $16.42 $18.14 $21.82 $24.84 $37.30
40‑49 mg $6.48 $7.70 $14.90 $17.06 $19.22 $22.97 $26.42 $39.82
50‑59 mg $6.77 $7.99 $17.06 $19.08 $21.02 $24.77 $28.22 $42.26
60‑79 mg $7.99 $9.22 $19.94 $21.82 $23.54 $28.22 $32.04 $48.02
80‑100 mg $8.28 $9.50 $23.54 $25.85 $28.22 $33.91 $37.73 $56.52
101‑200 mg $11.59 $13.30 $32.96 $36.18 $39.51 $47.48 $52.81 $79.13
201‑300 mg $13.25 $15.21 $37.67 $41.36 $45.16 $54.25 $60.37 $90.43
301‑400 mg $14.90 $17.10 $42.37 $46.53 $50.80 $61.04 $67.91 $101.74
401‑500 mg $15.73 $18.05 $44.73 $49.10 $53.62 $64.44 $71.68 $107.39
1000 mg $29.66 $30.89 $70.78 $77.69 $84.60 $101.66 $112.90 $169.42



  • The minimum charge per peptide is $200.00.
  • The above prices are per amino acid in the peptide and includes the cost for purification and mass spectrum analysis.
  • There are no hidden charges.
  • Please contact us for large scale peptide synthesis quote (from grams to kilograms).
  • The above pricing is valid for peptides 6-30aa in length. For other lengths or modifications please contact us at [email protected]

Additional Info

Our Custom Peptide Synthesis Service offers the following advantages:
High Quality Every single one of our custom peptides is analyzed by Mass Spectrum and HPLC. The quality control data will always be provided to you. We provide proof that your peptides were constructed correctly.
Competitive Pricing We will beat any other custom peptide provider's listed price.
Flexibility abm can synthesize any peptide in amounts ranging from milligrams to kilograms (Please ask for quote on amounts >1 gram).
Fast Delivery Time For most peptides of 6-30 amino acids in length, our typical turnaround time is about 3 weeks. This time may be extended for certain special peptides due to chemical challenges.
Available Modifications Peptide modifications are possible, please email your modification request to [email protected] for a custom quotation.

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FAQs


It is vitally important before you order your peptide to determine if it will be soluble in a medium that will be compatible with the experiments you wish to run.

1. Assign a value of -1 to each acidic residue that is Asp (D) or Glu (E), as well as the C-terminal–COOH (not present if peptide is made as an amide).

2. Assign a value of +1 to each basic residue that is Arg (R), Lys (K), His (H), or the N-terminal-NH2 (not present if the peptide was acetylated).

3. Add up the charges, thus determining the overall charge of the peptide.

4. For peptides with an overall charge of +1 or higher (a basic peptide), first try to dissolve the peptide in de-ionized water. If the peptide does not dissolve, add 10% acetic acid, drop-wise with vortexing in between. The peptide solution can also be warmed slightly. Longer peptides (20+ amino acids) with a small overall net charge might require the addition of a stronger acid. Trifluoroacetic acid (TFA 10-50µl) is often used to solubilize peptides but it is not cell-friendly and thus it is used only if acetic acid fails to help solubilize the peptide. After the addition of TFA, the peptide should be diluted to approximately 1ml with de-ionized water.

5. For peptides with an overall charge of less than zero (an acidic peptide), first try to dissolve the peptide in de-ionized water. If the peptide does not dissolve, add small amounts of 0.1 M ammonium bicarbonate and once in solution, dilute the peptide to approximately 1ml with deionized water. Note: Caution must be used, however, with peptides that contain cysteine (C), as an alkaline pH can cause disulfide bond formation.

6. For peptides with an overall charge of zero (a neutral peptide), solubilization may require the addition of various organic solvents, such as acetonitrile, DMSO, methanol, propanol or isopropanol. Denaturing salts, such as urea or guanidinium-HCL should only be used as a last resort.

Examples of peptides and their recommended solubilization methods:
  • VSRLGGKSIEVKIMPL [+4] + [-2] = +2 A basic peptide.
  • acetyl-VSRLGGKSIEVKIMPL-amide [+3)]+ [-1] = +2 A basic peptide.
  • acetyl-CGDLVGIKRETEYPRLAV [+3] + [-4] = -1 An acidic peptide but given the presence of cysteine, caution should be used. Thus, de-ionized water or a small amount of organic solvent should be tried first.


To summarize:
  • - If the sequence is basic in nature, then use 10% acetic acid to dissolve.
  • - If the sequence is acidic in nature, use 0.1 M ammonium bicarbonate to dissolve.
  • - If both ways above fail, use 20~30% DMSO and the peptide will dissolve.

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