CRISPR Genome Editing

Edit, tag, silence, or activate any part of the genome with unprecedented specificity with our CRISPR toolkit. Empower yourself with CRISPR today and make the genome your playground! abm has everything you need for all steps of your CRISPR experiment, from sgRNA design to screening and validation. Or, if you'd prefer, our expert scientists can perform the entire CRISPR knockout procedure for you.
"We are very happy with the product and the turn around time, and would therefore order another reagent."

Dr. Alexandra Duverger, University of Alabama at Birmingham, CRISPR

Search Library

CRISPR Library

We offer genome-wide libraries of sgRNAs for human, mouse, and rat genes in a full complement of viral and non-viral delivery systems, or ready-to-use CRISPR KO cell lines.

Resources

  • Introduction to CRISPR
    Introduction to CRISPR
    CRISPR Knowledge Base
  • CRISPR Methods and Tools
    CRISPR-Methods and Tools
    CRISPR Knowledge Base
  • sgRNA Design
    CRISPR-gRNA Design
    CRISPR Knowledge Base
  • CRISPR Gene Activation Repression
    CRISPR for Gene Activation and Repression
    CRISPR Knowledge Base
  • CRISPR Experimental Design Tool
    CRISPR Experiment Design Tool
    CRISPR Tools
  • CRISPR Knockout Manual
    CRISPR Knockout Manual
    CRISPR Guides/Manuals
  • CRISPR Case Studies
    CRISPR Case Studies
    CRISPR Guides/Manuals
  • CRISPR KO Results
    CRISPR KO Results
    Our data speaks for itself

Top Publications

01

Tumour-derived leukaemia inhibitory factor is a major driver of cancer cachexia and morbidity in C26 tumour-bearing mice.

Kandarian SC., et al.
J Cachexia Sarcopenia Muscle. (2018)


doi: 10.1002/jcsm.12346.

02

Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.

Kang, Y. J. et al.
Nat. Commun. (2015)


doi: 10.1038/ncomms9371

03

Isorhapontigenin (ISO) inhibits invasive bladder cancer (BC) formation in vivo and human BC invasion in vitro by targeting STAT1/FOXO1 Axis.

Jiang, G. et al.
Cancer Prev Res. (2016)


doi: 10.1158/1940-6207.CAPR-15-0338

Testimonials

We are quite happy with the knockout cells that you made. This was a tricky knockout and hemizygous removal was much more prevalent than the double knockout, but you did it. In addition to your excellent genomic sequence characterization of both mutant LIF alleles, I have confirmed in our lab that the tumor cells have lost all mouse LIF production.

Dr. Robert Jackman
Boston University

Mouse LIF CRISPR Knock Out C26 Tumor Cell Line Generation and Screening Service

Construct works beautifully, definitely will get more if needed.

Emily Chen
UCLA

CRISPR Lentivectors

The All-in-One Lentivectors worked very well.

Dr. Makoto Miyazaki
University of Colorado-Denver

CRISPR

Promotions

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  1. Sku: 1000112
    Price: $95.00~$495.00
    Unit: 1.0 μg per target, 300 μl
    This CRISPR activation sgRNA lentivector/lentivirus is designed to activate the 0610007C21Rik gene when paired with dCas9-SAM. sgRNAs are specially designed for use with the 0610007C21Rik gene in CRISPRa applications.


  2. Sku: 1000111
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610007C21Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  3. Sku: 1000212
    Price: $95.00~$495.00
    Unit: 1.0 μg per target, 300 μl
    This CRISPR activation sgRNA lentivector/lentivirus is designed to activate the 0610007L01Rik gene when paired with dCas9-SAM. sgRNAs are specially designed for use with the 0610007L01Rik gene in CRISPRa applications.


  4. Sku: 1000211
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610007L01Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  5. Sku: 1000312
    Price: $95.00~$495.00
    Unit: 1.0 μg per target, 300 μl
    This CRISPR activation sgRNA lentivector/lentivirus is designed to activate the 0610007P08Rik gene when paired with dCas9-SAM. sgRNAs are specially designed for use with the 0610007P08Rik gene in CRISPRa applications.


  6. Sku: 1000311
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610007P08Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  7. Sku: 1000412
    Price: $95.00~$495.00
    Unit: 1.0 μg per target, 300 μl
    This CRISPR activation sgRNA lentivector/lentivirus is designed to activate the 0610007P14Rik gene when paired with dCas9-SAM. sgRNAs are specially designed for use with the 0610007P14Rik gene in CRISPRa applications.


  8. Sku: 1000411
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610007P14Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  9. Sku: 1000512
    Price: $95.00~$495.00
    Unit: 1.0 μg per target, 300 μl
    This CRISPR activation sgRNA lentivector/lentivirus is designed to activate the 0610007P22Rik gene when paired with dCas9-SAM. sgRNAs are specially designed for use with the 0610007P22Rik gene in CRISPRa applications.


  10. Sku: 1000511
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610007P22Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...

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