Edit, tag, silence, or activate any part of the genome with unprecedented specificity with our CRISPR toolkit. Empower yourself with CRISPR today and make the genome your playground!
Right: ELISA measure of mouse LIF in cell-conditioned medium. Either wild type C26 mouse adenocarcinoma (C26) or CRISPR-derived mutants of these cells lacking the LIF gene (C26LIFKO cell line made by abm) were used to create conditioned medium. The wild type tumor cells secreted substantial levels of LIF into the medium while the knockout cells secreted undetectable or no LIF, an indication of correct CRISPR targeting in the cell line.
Data is courtesy of Dr. Robert Jackman (Boston University).
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Hailed as the biggest biotech breakthrough of this decade, the simple and effective CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) gene editing system is revolutionizing how research is performed and even how diseases may be treated in the near future. As a leader in genetic engineering and viral vector technology, abm is constantly searching for and developing the most innovative and affordable technologies. That’s why we’re offering a comprehensive repertoire of CRISPR tools—from Cas9 nucleases, nickases, and double mutants, to sgRNA libraries and knockout cell lines that can target every human, mouse, and rat gene.
Dr. Robert Jackman, Boston University, Mouse LIF CRISPR Knock Out C26 Tumor Cell Line Generation and Screening Service
Dr. Alexandra Duverger, University of Alabama at Birmingham, CRISPR
Dr. Makoto Miyazaki, University of Colorado-Denver, CRISPR
Emily Chen, UCLA, CRISPR Lentivectors
