CRISPR Genome Editing
Edit, tag, silence, or activate any part of the genome with unprecedented specificity with our CRISPR toolkit. Empower yourself with CRISPR today and make the genome your playground!
Genome-wide CRISPR sgRNA Vector/Virus
Choose from our collection of sgRNA vectors/viruses for knock-out of any human, mouse, or rat gene using our Cas9 system
Genome-wide CRISPR Activation sgRNA Vector/Virus
Choose from our collection of sgRNA vectors/viruses for use in the activation of any human, mouse, or rat gene using our dCas9-SAM system.
Cas9 Expressing
Stable Cell Lines
Select from our list of affordable, ready-to-use, constitutively expressing Cas9 cell lines.
Cas9 Vectors
and Viruses
Get the Cas9 nuclease, nickase, or null mutant with effector complex in a range of viral expression systems. Cumate-inducible also available.
Cas9 Proteins
Choose from our ready-to-use Cas9 nuclease, nickase, or null mutant proteins. NLS-tagged option is available.
Custom CRISPR
Knock-In Repair
Templates
Our Homology-Directed Repair (HDR) Templates are custom-made for the perfect CRISPR knock-in.
Anti-Cas9
Antibody
Our anti-Cas9 monoclonal antibody is the ideal complement to your CRISPR experiment.
More Gene Editing Tools
Right: ELISA measure of mouse LIF in cell-conditioned medium. Either wild type C26 mouse adenocarcinoma (C26) or CRISPR-derived mutants of these cells lacking the LIF gene (C26LIFKO cell line made by abm) were used to create conditioned medium. The wild type tumor cells secreted substantial levels of LIF into the medium while the knockout cells secreted undetectable or no LIF, an indication of correct CRISPR targeting in the cell line.
Data is courtesy of Dr. Robert Jackman (Boston University).
This handbook outlines guidelines for CRISPR sgRNA design and the experimental procedures needed to achieve a specific gene knockout in a mammalian cell system.
Simply fill in your email to download the CRISPR Knockout Manual:
Dr. Robert Jackman, Boston University, Mouse LIF CRISPR Knock Out C26 Tumor Cell Line Generation and Screening Service
Dr. Alexandra Duverger, University of Alabama at Birmingham, CRISPR
Dr. Makoto Miyazaki, University of Colorado-Denver, CRISPR
Emily Chen, UCLA, CRISPR Lentivectors
Protein Expression & Analysis
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