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Gene Expression Vectors, Viruses & Cloning Systems
abm is a world leader in recombinant viral technology, providing the most comprehensive collection of AAV-, lenti-, adeno- and retro-viral vectors in ready-to-use formats. This is in addition to the custom virus packaging services we offer, where we can package any custom made recombinant viral vector at any titer of the customer's choice.


Gene Regulation Vectors & Viruses
Gene regulation and functional studies can be made faster and simpler using tools like our siRNA, miRNA, lncRNA expression systems, as well as our miRNA target validation system, the 3'UTR Reporter platform. abm can also produce custom mutants, inhibitors, and targeted variants to further focus your studies.
 


CRISPR/Cas9 Genome Editing Tools
The latest RNA-guided endonuclease tool for genome editing is the Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 system, which allows for highly specific genomic disruption and replacement. We offer genome wide knockout sgRNA libraries, as well as different variants for Cas9 studies (Wild type, Nickase, Double mutant dCas9, and dCas9-SAM). abm has years of experience in custom knockout and knock-in cell line services, and we also offer gene activation by dCas9 fused to a tripartite synergystic activation modulator (dCas9-SAM).


Cell Immortalization & Stem Cell Research
Viral vectors have been the most widely used delivery vehicle for both cell immortalization and iPSC reprogramming due to their high efficiency of both transduction and stable integration. As a world leader in cell immortalization and stem cell research, abm provides the most comprehensive selection of vectors with choices of different promoters and genes such as TERT, SV40 T, CDK1, BMI1 and p53 for immortalization, and MYC, LIN28, OCT4, SOX2, KLF4, and NANOG for stem cell research.