Active Kinases

Active Kinases are highly regulated proteins that participate in complex network of various cell signalling pathways. abm offers a wide spectrum of Active Kinases for both functional studies and research efforts geared towards drug discovery. The Active Kinase products range from 70 to 90% in purity and are supplied as liquid formulations

Active Kinases

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  1. Price: $295.00
     WNK4 or WNK lysine deficient protein kinase 4 is a member of the WNK family of serine-threonine protein kinases which is part of the tight junction complex in kidney cells. WNK4 can regulate the balance between NaCl reabsorption and K(+)...


  2. Price: $295.00
    TXK or RLK is a member of the TEC family of non-receptor tyrosine kinases. TXK is expressed in T-cells and is an important component of signaling pathways downstream of lymphocyte antigen receptor. TXK is phosphorylated in response to T-cell...


  3. Price: $295.00
    TTBK2 or tau tubulin kinase 2 is a serine-threonine kinase that putatively phosphorylates tau and tubulin proteins. TTBK2 is a member of the casein kinase (CK1) group of eukaryotic protein kinases that is involved in tau phosphorylation and...


  4. Price: $295.00
    TGFBR2 is a member of the TGFbeta receptor subfamily and is a ser/thr protein kinase. TGFBR2-induced protein phosphorylation plays a key role in signal transduction that leads to mitogenic responses . The TGFBR2 receptor transmits signals from the...


  5. Price: $295.00
    TGFBR1 or transforming growth factor, beta-receptor 1 is a member of the TGFbeta receptor subfamily and is a ser/thr protein kinase that forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta...


  6. Price: $295.00
    TEC is a member of the Tec family of non-receptor protein-tyrosine kinases that are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin...


  7. Price: $295.00
     SRC family belongs to non-receptor tyrosine kinases. SRC was originally identified as a transforming protein of the Rous sarcoma virus (RSV) that had enzymatic ability to phosphorylate tyrosine in protein substrates . SRC is overexpressed and...


  8. Price: $205.00
    PKCa is a member of the protein kinase C (PKC) family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC-alpha has been reported to play roles in many different cellular...


  9. Price: $295.00
    PIM3 or pim-3 oncogene belongs to a family of protooncogenes that encode serine/threonine protein kinases . Pim-3 expressed in hepatocellular carcinoma development and plays a main role in the proliferation of human hepatoma cell lines . Pim-3 also...


  10. Price: $295.00
    PDGFRa (platelet-derived growth factor receptor A) is a member of the PDGFR family of membrane receptors with intrinsic tyrosine kinase activity. Aberrant expression of PDGFRa has been linked to developmental abnormalities in vertebrate models and...

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