Active Kinases

Active Kinases are highly regulated proteins that participate in complex network of various cell signalling pathways. abm offers a wide spectrum of Active Kinases for both functional studies and research efforts geared towards drug discovery. The Active Kinase products range from 70 to 90% in purity and are supplied as liquid formulations

Active Kinases

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  1. Sku: Z500001
    Price: $325.00
    Unit: 10 µg
     ABL1 protooncogene encodes a cytoplasmic and nuclear protein tyrosine kinase that has been implicated in processes of cell differentiation, cell division, cell adhesion, and stress response. Activity of ABL protein is negatively regulated by its...


  2. Sku: Z500002
    Price: $325.00
    Unit: 10 µg
    ABL2 (or ARG) is a nonreceptor cytoplasmic tyrosine kinase which is closely related to but distinct from ABL1. The similarity of ABL1 and ABL2 includes the tyrosine kinase domains and extends amino-terminal to include the SH2 and SH3 domains. ABL2...


  3. Sku: Z500003
    Price: $325.00
    Unit: 10 µg
    ACK is a tyrosine kinase that binds CDC42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of CDC42Hs . Overexpression of ACK in cancer cell lines of epithelial origin increases...


  4. Sku: Z500004
    Price: $235.00
    Unit: 10 µg
    AKT1/PKBa is a serine/threonine kinase that belongs to the AKT family. AKT1 is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix components and is involved in glucose metabolism,...


  5. Sku: Z500005
    Price: $325.00
    Unit: 10 µg
    AKT2 or Protein Kinase B ß (PKBß) is a serine/threonine kinase that is a member of the AKT family. AKT2 like the other AKT members is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix...


  6. Sku: Z500006
    Price: $325.00
    Unit: 10 µg
    AKT2 or Protein Kinase B ß (PKBß) is a serine/threonine kinase that is a member of the AKT family. AKT2 like the other AKT members is activated in cells in response to diverse stimuli such as hormones, growth factors and extracellular matrix...


  7. Sku: Z500007
    Price: $325.00
    Unit: 10 µg
     AKT 3 or Protein Kinase B ? (PKB?) is a serine/threonine kinase that is a member of the AKT family. AKT 3 is activated in cells exposed to diverse stimuli such as hormones, growth factors, and extracellular matrix components . AKT 3 phosphorylates...


  8. Sku: Z500008
    Price: $325.00
    Unit: 10 µg
     ALK or anaplastic lymphoma kinase is a receptor tyrosine kinase that was originally identified as a member of the insulin receptor subfamily that acquires transforming capability when truncated and fused to NPM (nucleophosmin) in the t(2;5)...


  9. Sku: Z500009
    Price: $325.00
    Unit: 10 µg
     ALK1 is a serine/threonine-protein kinase receptor R3 precursor that mediates signal by TGFß superfamily . ALK1 functions as a TGFß type I receptor in endothelial cells and is responsible for human hereditary hemorrhagic telangiectasia (HHT)...


  10. Sku: Z500010
    Price: $325.00
    Unit: 10 µg
    ALK 2 is a receptor serine/threonine kinase that is member of the ALK family and is upstream of signaling pathway involving the SMAD proteins especially SMAD1/5/8. Knockdown of ALK2, but not TGFßRI (ALK5), abrogates endoglin-mediated decrease in...

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