CRISPR Knockout AAV Library

abm's CRISPR Knockout sgRNA AAV Viruses have a broad host range and low immunogenicity, perfect forin vivoCRISPR experiments. AAV is non-integrating, so there is less risk of interfering with host gene expression. We offer a collection of Knockout AAVs that express sgRNAs targeting any human, mouse, or rat gene, compatible with either spCas9 or saCas9. In addition to sgRNA-only vectors, we also offer an All-In-One AAV option, which expresses sgRNA and saCas9 nuclease from the same vector.

Key Features

  • Collection of sgRNAs for knockout of your gene of interest with either saCas9 or spCas9. Human, mouse, and rat gene targets are available.
  • AAV delivery for low immunogenicity and non-integrating expression of sgRNA and/or saCas9.
  • Available expressing sgRNA alone, or as an All-In-One construct which expresses both sgRNA and saCas9.
  • Comes as a set or pool of three sgRNA AAVs for assurance of efficient gene knockout.
  • Available as AAV serotypes 1 to 11 for high transduction efficiency in specific tissues.

For multiplex gRNA expression from lentiviral vector, use our Custom Multiplex gRNA Service.
For knockout of up to 100 target genes, take advantage of our pooled Custom Targeted Lentiviral sgRNA Library Service.

Search Knockout sgRNA Library

Knockout sgRNA Library

We offer sgRNA and all-in-one AAVs for knockout of any human, mouse, or rat gene.



Product Information

  • CRISPR Knockout Case Study
    Performance/Data
    Click to see our CRISPR Knockout Case Study, including experimental design and supporting data.
  • CRISPR AAV Workflow
    Workflow
    How to use abm's sgRNA AAVs in your CRISPR knockout experiment.
  • CRISPR Knockout Guide
    Need Help Getting Started?
    This handbook outlines guidelines for CRISPR sgRNA design and the experimental procedures needed to achieve a specific gene knockout.

Top Publications

Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.

Kang, Y J et al.
Nat. Commun. 6:8371 (2015).


DOI: 10.1038/ncomms9371.

Isorhapontigenin (ISO) inhibits invasive bladder cancer (BC) formation in vivo and human BC invasion in vitro by targeting STAT1/FOXO1 Axis.

Jiang, G. et al.
Cancer Prev Res. Published Online First April 14, 2016.


doi: 10.1158/1940-6207.CAPR-15-0338

Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer.

Okugawa, Y et al.
Gut (2015)


doi:10.1136/gutjnl-2015-309359

Browse Products

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  1. Sku: 1000111
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610007C21Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  2. Sku: 1000211
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610007L01Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  3. Sku: 1000311
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610007P08Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  4. Sku: 1000411
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610007P14Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  5. Sku: 1000511
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610007P22Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  6. Sku: 1000611
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610009B22Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  7. Sku: 1000711
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610009D07Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  8. Sku: 1000811
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610009O20Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  9. Sku: 1000911
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610010B08Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...


  10. Sku: 1001011
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's 0610010F05Rik knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the...

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