CRISPR Knockout AAV Library

abm's CRISPR Knockout sgRNA AAV Viruses have a broad host range and low immunogenicity, perfect forin vivoCRISPR experiments. AAV is non-integrating, so there is less risk of interfering with host gene expression. We offer a collection of Knockout AAVs that express sgRNAs targeting any human, mouse, or rat gene, compatible with either spCas9 or saCas9. In addition to sgRNA-only vectors, we also offer an All-In-One AAV option, which expresses sgRNA and saCas9 nuclease from the same vector.

Key Features

  • Collection of sgRNAs for knockout of your gene of interest with either saCas9 or spCas9. Human, mouse, and rat gene targets are available.
  • AAV delivery for low immunogenicity and non-integrating expression of sgRNA and/or saCas9.
  • Available expressing sgRNA alone, or as an All-In-One construct which expresses both sgRNA and saCas9.
  • Comes as a set or pool of three sgRNA AAVs for assurance of efficient gene knockout.
  • Available as AAV serotypes 1 to 11 for high transduction efficiency in specific tissues.

For multiplex gRNA expression from lentiviral vector, use our Custom Multiplex gRNA Service.
For knockout of up to 100 target genes, take advantage of our pooled Custom Targeted Lentiviral sgRNA Library Service.

Search Knockout sgRNA Library

Knockout sgRNA Library

We offer sgRNA and all-in-one AAVs for knockout of any human, mouse, or rat gene.



Product Information

  • CRISPR Knockout Case Study
    Performance/Data
    Click to see our CRISPR Knockout Case Study, including experimental design and supporting data.
  • CRISPR AAV Workflow
    Workflow
    How to use abm's sgRNA AAVs in your CRISPR knockout experiment.
  • CRISPR Knockout Guide
    Need Help Getting Started?
    This handbook outlines guidelines for CRISPR sgRNA design and the experimental procedures needed to achieve a specific gene knockout.

Top Publications

Regulation of NKT cell-mediated immune responses to tumours and liver inflammation by mitochondrial PGAM5-Drp1 signalling.

Kang, Y J et al.
Nat. Commun. 6:8371 (2015).


DOI: 10.1038/ncomms9371.

Isorhapontigenin (ISO) inhibits invasive bladder cancer (BC) formation in vivo and human BC invasion in vitro by targeting STAT1/FOXO1 Axis.

Jiang, G. et al.
Cancer Prev Res. Published Online First April 14, 2016.


doi: 10.1158/1940-6207.CAPR-15-0338

Clinical significance of SNORA42 as an oncogene and a prognostic biomarker in colorectal cancer.

Okugawa, Y et al.
Gut (2015)


doi:10.1136/gutjnl-2015-309359

Browse Products

Showing 1-10 of 36356

Page
per page
Set Descending Direction

  1. Sku: 6922711
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's ZWS1 knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the ZWS1 gene. Also...


  2. Sku: 6922611
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's ZWINTAS knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the ZWINTAS gene....


  3. Sku: 6922211
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's ZSCAN12L1 knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the ZSCAN12L1...


  4. Sku: 6921011
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's ZNF864P knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the ZNF864P gene....


  5. Sku: 6920911
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's ZNF850P knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the ZNF850P gene....


  6. Sku: 6920811
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's ZNF838 knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the ZNF838 gene....


  7. Sku: 6920711
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's ZNF834 knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the ZNF834 gene....


  8. Sku: 6920611
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's ZNF833 knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the ZNF833 gene....


  9. Sku: 6920511
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's ZNF828 knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the ZNF828 gene....


  10. Sku: 6920411
    Price: $85.00~$5,660.00
    Unit: 1.0 μg per target, 5 x 200 μl, 300 μl per target, 1.0 ml, 1 x 106 cells/1.0 ml
    abm's ZNF826 knockout sgRNA vectors, viruses, and cell lines are ready to use in your CRISPR experiment. These knockout sgRNA vectors and viruses can be used in conjunction with Cas9 to perform high efficiency CRISPR knockouts of the ZNF826 gene....

Showing 1-10 of 36356

Page
per page
Set Descending Direction