Cas9 Expression Vectors and Viruses

abm offers the widest array of Cas9 vectors and viruses on the market, from spCas9 and saCas9 nucleases to null mutants and nickases, in a variety of viral delivery systems. And now available are vectors expressing dCas9 fused to effector domains for gene activation or repression (dCas9-SAM and dCas9-KRAB).

Pair our Cas9 products with an sgRNA expression vector or virus from our ready-to-use genome-wide knockout collection or activation collection. For CRISPR knock-in experiments, we offer ready-to-use repair templates.

 

Our Cas9 collection includes:

TypeDescriptionKnowledge Base
Cas9 Nuclease High-efficiency CRISPR genome editing nuclease available as spCas9 or saCas9 (smaller than spCas9 and suitable for packaging into AAV expression systems). Read more about different Cas9 nucleases here.
Cas9 Nickase Generates single-stranded nicks at target site for repair via the Homology Directed Repair (HDR) pathway to minimize off-target cleavage effects. Read more about Cas9 nickases here.
Cas9 Double Mutant (null mutant, dCas9) Cas9 with non-functional cleavage domains but with gene targeting function via sgRNA still intact. Useful as a tool for reversible knockdown of gene expression. Read more about Cas9 null mutants here.

 

Other CRISPR Delivery Tools:

Looking for our CRISPR Cas9+sgRNA ready-to-use knockout vectors and viruses? Click here.

Looking for our Cas9 recombinant protein collection? Click here.

Need recommendations on which CRISPR components you need for your experiment? Try our CRISPR Experimental Design Tool.

 

  • Experimental Design Tool
    CRISPR Experimental Design Tool
    Experimental recommendations tailored to your model system.
  • Workflow
    Workflow
    View our simplified workflow for performing CRISPR Cas9.
  • Knowledge Base
    Knowledge Base
    Learn about CRISPR Cas9 Methods and Tools.

Browse Products

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  1. Sku: K012
    Price: $395.00
    Unit: 10 µg
    This Cas9 Double Mutant (dCas9) has changes at amino acid positions D10A and H840A which completely inactivate both the nuclease and nickase activities. With a target-specific guide RNA (sgRNA), it can bind to a specific region of DNA without...


  2. Sku: K013
    Price: $695.00
    Unit: 300 µl
    This Cas9 Double Mutant (dCas9) has changes at amino acid positions D10A and H840A which completely inactivate both the nuclease and nickase activities. With a target-specific guide RNA (sgRNA), it can bind to a specific region of DNA without...


  3. Sku: K007
    Price: $295.00
    Unit: 250 µl
    This Cas9 nickase can be used with two target-specific sgRNAs to bind DNA and create two single-stranded cuts. Due to the requirement for two sgRNA guide sequences to be close together for gene editing to occur, using Cas9 nickase should cause fewer...


  4. Sku: K005
    Price: $85.00
    Unit: 10 µg
    This Cas9 nickase can be used with two target-specific sgRNAs to bind DNA and create two single-stranded cuts. Due to the requirement for two sgRNA guide sequences to be close together for gene editing to occur, using Cas9 nickase should cause fewer...


  5. Sku: K006
    Price: $295.00
    Unit: 300 µl
    This Cas9 nickase can be used with two target-specific sgRNAs to bind DNA and create two single-stranded cuts. Due to the requirement for two sgRNA guide sequences to be close together for gene editing to occur, using Cas9 nickase should cause fewer...


  6. Sku: K004
    Price: $295.00
    Unit: 250 µl
    This Cas9 nuclease can be used with a target-specific sgRNA to bind DNA and create a double-stranded cut.


  7. Sku: K002
    Price: $85.00
    Unit: 10 µg
    This Cas9 nuclease can be used with a target-specific sgRNA to bind DNA and create a double-stranded cut.


  8. Sku: K003
    Price: $295.00
    Unit: 300 µl
    This Cas9 nuclease can be used with a target-specific sgRNA to bind DNA and create a double-stranded cut.


  9. Sku: K095
    Price: $85.00
    Unit: 10 μg
    This Cas9 nuclease can be used with a target-specific sgRNA to bind DNA and create a double-stranded cut. It is provided in a non-viral vector (plasmid) for quick and easy transfection. Transfection will result in transient expression of Cas9,...


  10. Sku: K014
    Price: $545.00
    Unit: 10 µg
    This Cas9 Double Mutant (dCas9) has changes at amino acid positions D10A and H840A which completely inactivate both the nuclease and nickase activities. With a target-specific guide RNA (sgRNA), it can bind to a specific region of DNA without...

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