Cell Biology
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Christine Ott, University of Delaware, DNAfectin Plus (G2500)
doi: 10.1021/acschembio.7b00543
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Top Publications
MicroRNA-9 inhibits hyperglycemia-induced pyroptosis in human ventricular cardiomyocytes by targeting ELAVL1.
Jeyabal, P., et al.
Biochem Biophys Res Commun.
doi: 10.1016/j.bbrc.2016.02.065.
NBR1 enables autophagy-dependent focal adhesion turnover.
Kenific, CM., et al.
J Cell Biol. (2016) 212(5): 577-90. (2016)
doi: 10.1083/jcb.201503075.
Characterizing primary human microglia: A comparative study with myeloid subsets and culture models.
Melief, J., et al.
Glia. (2016) 64(11): 1857-68.
doi:10.1002/glia.23023.
Testimonials
ABM has always been very helpful with technical assistance in any of our questions and concerns. I also consider the price for the services provided as very competitive, as other companies charge a multiple of ABM's price. I would highly recommend ABM's service to any customer interested in custom-made pluripotent stem cells.
Dr. Cameron Moshfegh
ETH Zurich
iPSC Generation
I really like to order from ABM as the ordering process is fairly straight forward and the documentation provided, especially with the cell lines, is very well detailed and complete.
Nancy Petitclerc
Immuni T
Immortalized Cell Lines
We are quite happy with the knockout cells that you made. This was a tricky knockout and hemizygous removal was much more prevalent than the double knockout, but you did it. In addition to your excellent genomic sequence characterization of both mutant LIF alleles, I have confirmed in our lab that the tumor cells have lost all mouse LIF production.
Dr. Robert Jackman
Boston University
Mouse LIF CRISPR Knock Out C26 Tumor Cell Line Generation and Screening Service
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- In stock
InquireOmega-3 polyunsaturated fatty acids (ω3-PUFAs) are known to inhibit carcinogenesis, tumour growth and metastasis, whereas omega-6 polyunsaturated fatty acids (ω6-PUFAs) stimulate their effects. The FAT1 gene of C. elegans encodes a...
- In stock
InquireOmega-3 polyunsaturated fatty acids (ω3-PUFAs) are known to inhibit carcinogenesis, tumour growth and metastasis, whereas omega-6 polyunsaturated fatty acids (ω6-PUFAs) stimulate their effects. The FAT1 gene of C. elegans encodes a...
- In stock
InquireOmega-3 polyunsaturated fatty acids (ω3-PUFAs) are known to inhibit carcinogenesis, tumour growth and metastasis, whereas omega-6 polyunsaturated fatty acids (ω6-PUFAs) stimulate their effects. The FAT1 gene of C. elegans encodes a...
- In stock
InquireOmega-3 polyunsaturated fatty acids (ω3-PUFAs) are known to inhibit carcinogenesis, tumour growth and metastasis, whereas omega-6 polyunsaturated fatty acids (ω6-PUFAs) stimulate their effects. The FAT1 gene of C. elegans encodes a...
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InquireSIRT7 Stable Scramble H1299 Cell Line was generated by lentiviral driven expression of shRNAs. Lack of Sirt7 is associated with reduced recruitment of DNMT1 and Sirt1 at rRNA genes leading to hyperacetylation of histones, reduced DNA methylation,...
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InquireSIRT7 Stable Scramble HeLa Cell Line was generated by lentiviral driven expression of shRNAs. Lack of Sirt7 is associated with reduced recruitment of DNMT1 and Sirt1 at rRNA genes leading to hyperacetylation of histones, reduced DNA methylation,...
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Inquireβ-Actin (ACTB) was integrated into a specific genomic loci using CRISPR/Cas9 in HEK293T cells. The transgene is driven by endogenous promoters to ensure consistent and predictable expression of ACTB. A protein quantification reporter (PQR) was...
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InquireBRCA1 is a tumor suppressor gene that plays a significant role in DNA repair pathways. Human fibroblast cells were transfected with CRISPR/Cas9 plasmids which target BRCA1 to generate the BRCA1 CRISPR Stable Knockout Human Fibroblast Cell Line. This...
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InquireMuscarinic type 3 receptor (M3R) is the primary receptor subtype to promote fluid secretion in salivary acinar cells. Research has shown that anti-M3R autoantibodies (anti-M3R) are potential inhibitors of saliva secretion in Sjögren's syndrome...
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InquireAXL CRISPR Stable Knockout HT1080 (3-II) Cell Line was developed to aid in the study with AXL biological roles. AXL is a tyrosine kinase receptor and is involved in pathways and in cellular functions such as growth, migration, or aggregation. Some...