Drug Discovery Cell Lines
Leverage abm’s proven success in the generation and validation of stable cell lines to accelerate your novel drug discoveries and biomedical research. Fully-validated, we have generated a unique collection of G protein-coupled receptors (GPCR), Kinases, nuclear hormone receptors (NHR) and ion channel stable cell lines to provide powerful assay platforms for all research projects.
As a leader in gene expression and recombinant viral technology, we have streamlined the workflow from DNA construct cloning and recombinant viral vector generation/packaging to gene expression quality control and stable cell line generation for every gene in the human, mouse and rat genome. With our custom-tailored whole genome Stable Cell Line solutions, the most difficult challenges in stable cell line creation can be overcome — so you can focus on answering the bigger questions in your project.
Search Drug Discovery Cell Lines Collection
Drug Discovery Cell Lines Collection
We offer wide selection of human, mouse, rat, and hamster drug discovery cell lines across more than 10 different cell systems.
|01||Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[18F]Fluoro-d-Glucose Uptake in Prostate Cancer Mouse Xenografts.
Schlaepfer, I. R et al
Molecular Imaging and Biology 4:529-538 (2015).
|Why do these cells need bio safety level II?|
In order to be more cautious, we follow the CDC-NIH recommendations that all mammalian sourced products should be handled at the Biological Safety Level 2 to minimize exposure of potentially infectious products. This information can be found in 'Biosafety in Microbiological and Biomedical Laboratories' (1999). Your institution's Safety Officer or Technical Services will be able to make the call as to whether BioSafety Level I is possible with these cells at your site if required.
|How do you test for the presence of replication incompetent lentivirus in these cell line products?|
We perform this QC by testing viral titer of the culture media from each b atch using abm's qPCR titer kit (Cat# LV900), the results for which can be provided on the CoA for each lot#, upon request.
|How long can I store frozen vials for?|
Cells that are properly frozen using an effective cryoprotective agent can be stored in liquid nitrogen indefinitely without affecting their recovery.
Showing 1-10 of 724
- Sku: T6352
Unit: 1x106 cells / 1.0 mlMicroRNAs (miRNAs) comprise a class of small non-coding RNAs that regulate the stability and/or translatability of most protein-coding transcripts. They guide AGO proteins within the RNA-induced silencing complex (RISC) and plays a part to degrade...
- In stockSku: T3170
Unit: 1x106 cells / 1.0 ml88 TAg Stable Y-LIZ DNA Polymerase-β Knockout Mouse Embryonic Fibroblast Cell Line carries the lambda-LIZ transgene (Y-LIZ), a shuttle vector which enables for mutation analysis. The 92 TAg is the wild type cell line to the polymerase beta knock...
- In stockSku: T3169
Unit: 1x106 cells / 1.0 ml92 TAg Stable Y-LIZ Wildtype Mouse Embryonic Fibroblast Cell Line carry the lambda-LIZ transgene (Y-LIZ), a shuttle vector which enables for mutation analysis. The 92 TAg is the wild type cell line to the polymerase beta knock out cells available at...
- Sku: T6473
Unit: 1x106 cells / 1.0 ml
- Sku: T3017
Unit: 1x106 cells / 1.0 ml
- Sku: T6454
Unit: 1x106 cells / 1.0 mlThrough lentiviral infection, the A30P aSYN-IRES-GFP Stable LUHMES Cell Line was generated. The cells stably express A30P aSyn. This cell line can be used to study neurotoxicity and to identify targets for treatment/prevention of neurodegenerative...
- Sku: T6455
Unit: 1x106 cells / 1.0 mlThrough lentiviral infection, the A53T aSYN-IRES-GFP Stable LUHMES Cell Line was generated. The cells stably express A53T aSyn. This cell line can be used to study neurotoxicity and to identify targets for treatment/prevention of neurodegenerative...
- Sku: T3235
Unit: 1x106 cells / 1.0 mlA549 cells constituitvely expressing ACE2 and TMPRSS2. A sleeping beauty transposon system was used to generate this cell line which is highly susceptible to SARS-CoV-2. Therefore, the cell line is an excellent model for rapid and sensitive...
- Sku: T6541
Unit: 1x10⁶ cells / 1.0 mlPrimary mouse embryonic fibroblasts (MEFs) were isolated from 14.5-day-old embryos and, where indicated, transformed by SV40 T-antigen expression. Knockout of AAG mouse cell line which can be used to study the DNA repair and DNA damage checkpoint...
- Sku: T3134
Unit: 1x106 cells / 1.0 mlFusing a kinase domain to a homodimerization domain such as the PNT domain of ETV6 can result in activated kinase. The AATK Stable Ba/F3 Cell Line expresses activated AATK tyrosine kinase that is linked to a GFP reporter (GFP-ETV6-AATK in MSCV-puro...