Drug Discovery Cell Lines

Leveraging abm’s proven success in the generation and validation of stable cell lines to accelerate your novel drug discoveries and biomedical research. Fully-validated, we have generated an unique library collection of G protein-coupled receptor (GPCR), Kinase, nuclear hormone receptor (NHR) and ion channel stable cell lines to provide powerful assay platforms for all research projects.

As a leader in gene expression and recombinant viral technology, we have streamlined the workflow from DNA construct cloning to recombinant viral vector generation and packaging, to gene expression quality control and to stable cell line generation for every gene in the human, mouse and rat genome. With our custom-tailored Whole-Genome Stable Cell Line solutions, the most difficult challenges in stable cell line creation can be overcome — so you can focus on answering the bigger questions in your project.

Search Drug Discovery Cell Lines Collection

Drug Discovery Cell Lines Collection

We offer wide selection of human, mouse, rat, and hamster drug discovery cell lines across more than 10 different cell systems.



Product Information

  • Characterization of BRITER cell line
    Characterization of BRITER cell line
    Characterization of the BRITER Cell Line (T3105), which has a BMP Response Element-dependent Firefly Luciferase gene.
  • cell culture workflow
    Cell Culture Workflow
    The SUNE2 cell line is derived from a nasopharyngeal carcinoma (NPC) from the biopsy performed on a 38-year-old female Cantonese patient.
  • Custom Stable Cell Line Generation Workflow
    Custom Stable Cell Line Generation Service
    abm provides a high quality and a cost-effective service for creating a cell line expressing your gene of interest with a fast turnaround time.

Top Publications

01 Inhibition of Lipid Oxidation Increases Glucose Metabolism and Enhances 2-Deoxy-2-[18F]Fluoro-d-Glucose Uptake in Prostate Cancer Mouse Xenografts.

Schlaepfer, I. R et al
Molecular Imaging and Biology 4:529-538 (2015).


DOI: 10.1007/s11307-014-0814-4.
02 Characterization of ryanodine receptor type 1 single channel activity using "on-nucleus" patch clamp.

Wagner, LE et al
Cell Calcium 56(2):96-107 (2014)


DOI: 10.1016/j.ceca.2014.05.004.

FAQs

Why do these cells need bio safety level II?
In order to be more cautious, we follow the CDC-NIH recommendations that all mammalian sourced products should be handled at the Biological Safety Level 2 to minimize exposure of potentially infectious products. This information can be found in 'Biosafety in Microbiological and Biomedical Laboratories' (1999). Your institution's Safety Officer or Technical Services will be able to make the call as to whether BioSafety Level I is possible with these cells at your site if required.
How do you test for the presence of replication incompetent lentivirus in these cell line products?
We perform this QC by testing viral titer of the culture media from each b atch using abm's qPCR titer kit (Cat# LV900), the results for which can be provided on the CoA for each lot#, upon request.
How long can I store frozen vials for?
Cells that are properly frozen using an effective cryoprotective agent can be stored in liquid nitrogen indefinitely without affecting their recovery.

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  1. Sku: T6352
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    Unit: 1x106 cells / 1.0 ml
    MicroRNAs (miRNAs) comprise a class of small non-coding RNAs that regulate the stability and/or translatability of most protein-coding transcripts. They guide AGO proteins within the RNA-induced silencing complex (RISC) and plays a part to degrade...


  2. Sku: T3170
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    Unit: 1x106 cells / 1.0 ml
    88 TAg Stable Y-LIZ DNA Polymerase-β Knockout Mouse Embryonic Fibroblast Cell Line carries the lambda-LIZ transgene (Y-LIZ), a shuttle vector which enables for mutation analysis. The 92 TAg is the wild type cell line to the polymerase beta knock...


  3. Sku: T3169
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    Unit: 1x106 cells / 1.0 ml
    92 TAg Stable Y-LIZ Wildtype Mouse Embryonic Fibroblast Cell Line carry the lambda-LIZ transgene (Y-LIZ), a shuttle vector which enables for mutation analysis. The 92 TAg is the wild type cell line to the polymerase beta knock out cells available at...


  4. Sku: T3017
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    Unit: 1x106 cells / 1.0 ml


  5. Sku: T6454
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    Unit: 1x106 cells / 1.0 ml
    Through lentiviral infection, the A30P aSYN-IRES-GFP Stable LUHMES Cell Line was generated. The cells stably express A30P aSyn. This cell line can be used to study neurotoxicity and to identify targets for treatment/prevention of neurodegenerative...


  6. Sku: T6455
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    Unit: 1x106 cells / 1.0 ml
    Through lentiviral infection, the A53T aSYN-IRES-GFP Stable LUHMES Cell Line was generated. The cells stably express A53T aSyn. This cell line can be used to study neurotoxicity and to identify targets for treatment/prevention of neurodegenerative...


  7. Sku: T3134
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    Unit: 1x106 cells / 1.0 ml
    Fusing a kinase domain to a homodimerization domain such as the PNT domain of ETV6 can result in activated kinase. The AATK Stable Ba/F3 Cell Line expresses activated AATK tyrosine kinase that is linked to a GFP reporter (GFP-ETV6-AATK in MSCV-puro...


  8. Sku: T6998
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    Unit: 1x106 cells / 1.0 ml
    This cell line is a suitable transfection host and is useful for influenza research.?These cells can be used for cell-cell adhesion studies, cell motility, cell polarity studies, and growth factor studies. The ABCG2 and ABCB1 genes are part of the...


  9. Sku: T3100
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    Unit: 1x106 cells / 1.0 ml
    Fusing a kinase domain to a homodimerization domain such as the PNT domain of ETV6 can result in activated kinase. The ABL1 Stable Ba/F3 Cell Line expresses activated ABL1 tyrosine kinase that is linked to a GFP reporter (GFP-ETV6-ABL1 in a...


  10. Sku: T3101
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    Unit: 1x106 cells / 1.0 ml
    Fusing a kinase domain to a homodimerization domain such as the PNT domain of ETV6 can result in activated kinase. The ABL2 Stable Ba/F3 Cell Line expresses activated ABL2 tyrosine kinase that is linked to a GFP reporter (GFP-ETV6-ABL2 in SED2...

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