iPSC Small Molecules
Induced pluripotent stem cell (iPSC) generation, a valuablel tool in stem cell research, has traditionally been achieved by the over expression of four of the six iPSC transcription factors. Recent studies, however, have shown that some genetic function of these six iPSC transcription factors required for iPSC generation can be substituted by defined small chemical molecules. Now we know that some small molecules are the key to directly controlling stem cell development and could contribute to the advancement of tissue repair and regeneration.
ABM developed and distributes small chemical compunds that have been shown to play a role in stem cell and iPSC research. All our molecules are of the highest purity (≥98%), structurally verified by NMR and mass spectrometry, and tested for cytotoxicity.