Question (2240)
Question
Do immortalized cells retain all characteristics of the original primary cell line?
ABM community
Verified customer
Asked on Aug 11 2025
Answer
Not always. Some phenotypic or genetic changes may occur during immortalization. We recommend using our hTERT immortalization reagents as this method preserves phenotype and karyotype as well as minimizes genomic instability.
ABM Scientific Support
Answered on Aug 11 2025