CMV Control Apoptosis Adenovirus
| Cat. No. | G3000 |
| Name | CMV Control Apoptosis Adenovirus |
| Unit | 1.0 ml |
| Description |
abm’s Targeted Cell Apoptosis Adenoviruses provide a targeted clean-up step for iPSC workflows, enabling inducible, selective depletion of non-reprogrammed and off-target cells. These recombinant adenoviruses transiently deliver a construct in which a cell type-specific promoter drives expression of an inducible caspase. After transduction, addition of the small molecule Rimiducid (AP1903) or AP20187 activates apoptosis specifically in targeted cell populations, resulting in efficient depletion of residual somatic cells and enrichment of a purified iPSC population. Features:
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| Applications |
•iPSC post-reprogramming population enrichment |
| Titer | >1 x 106 pfu/ml |
| Storage Condition | Storage Buffer: DMEM with 10% glycerol. Upon arrival, store the viruses at -80°C in small aliquots to avoid repeated freeze-thaw cycles. |
| Note |
•Yamanaka factors (OSKM) are not included. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. G3000 |