CHIR99021

CAT.NOUNITPRICE
G6112.0 mg
$60.00

Specifications


SKUG611
Concentration10mM in DMSO (~430ul)
Formal Name6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile
FormulaC22H18Cl2N8
Purity99%
CautionFor Research Use Only, not for therapeutic or diagnostic purposes.
FunctionGlycogen synthase kinase 3β (GSK3β) inhibitor that has antiproliferative activity in vitro and in vivo.
Small Molecule ActionReprogramming
Molecular Weight465g/mol
Unit quantity2.0 mg
Stability2 years
Storage Condition

-20°C

Shipping Conditions

On Wet Ice

QC

MR and Mass Spectrometry

Documents


Supporting Protocol

    MSDS

      QC

        Other

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          References


          1
          • Shen, J., Lyu, C., Zhu, Y., Feng, Z., Zhang, S., Hoyle, D. L., … Wang, Z. Z. "Defining early hematopoietic‐fated primitive streak specification of human pluripotent stem cells by the orchestrated balance of Wnt, activin, and BMP signaling" Journal of Cellular Physiology 234(9):16136–16147 (2019). DOI: 10.1002/jcp.28272.