Cas Proteins & CRISPR Screening

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CRISPR is the most versatile technology for genome editing and abm offers the largest selection of Cas9 proteins for CRISPR experiments. Cas9 Ribonucleoproteins (RNPs) are Cas9 proteins in complex with in vitro transcribed sgRNA. These RNPs can be used for in vitro pre-screening sgRNA candidates and can be directly transfected or electroporated into cells to achieve gene editing.

Advantages of Cas9 RNP Delivery Method:

No transcription or translation required, thus editing is rapid and transient
No plasmid or virus is used, therefore no risk of genome integration of Cas9/sgRNA machinery
Proteins are compatible with a wide range of organisms, no need to consider promoters & codon optimization

abm is continually developing a range of CRISPR-Cas proteins, while also advancing high-fidelity options for precise genetic editing.

We also offer CRISPR screening kits that efficiently verify gene editing, saving valuable time, along with an sgRNA synthesis kit that includes all the necessary reagents for high-yield RNA transcription, ensuring seamless preparation for downstream CRISPR experiments.

Visit our knowledge base for more information about CRISPR-related technology.

Product Name	Cat. No.	Quantity	Price
spCas9 Nuclease
Cas9 Nuclease Protein	K108	40 µg (250 pmol/25 µL)	$80.00TEST
Cas9 Nuclease NLS Protein	K030	8.0 µg (50 pmol/50 µL)	$40.00
Cas9 Nuclease NLS Protein (High Concentration)	K130	40 µg (250 pmol/25 µL)	$80.00
Cas9 Nuclease NLS Protein (Lyophilized)	K151	200 µg (1.25 nmol)	$295.00
spCas9 Nickase
Cas9 Nickase D10A Protein	K132	40 µg (250 pmol/25 µL)	$135.00
Cas9 Nickase D10A NLS Protein	K134	40 µg (250 pmol/25 µL)	$135.00
Cas9 Nickase H840A Protein	K136	40 µg (250 pmol/25 µL)	$135.00
Cas9 Nickase H840A NLS Protein	K138	40 µg (250 pmol/25 µL)	$135.00
spCas9 Null Mutant
Cas9 Null Mutant Protein	K140	40 µg (250 pmol/25 µL)	$135.00
Cas9 Null Mutant NLS Protein	K142	40 µg (250 pmol/25 µL)	$135.00
spCas9 GFP
Cas9 Nuclease GFP NLS Protein	K048	9.5 µg (50 pmol/50 µL)	$55.00
Cas9 Nuclease GFP NLS Protein (High Concentration)	K148	47 µg (250 pmol/25 µL)	$155.00
Cas9 Nickase D10A GFP NLS Protein	K149	47 µg (250 pmol/25 µL)	$155.00
Cas9 Null Mutant GFP NLS Protein	K086	9.5 µg (50 pmol/50 µL)	$55.00
Cas9 Null Mutant GFP NLS Protein (High Concentration)	K186	47 µg (250 pmol/25 µL)	$155.00
saCas9 Nuclease
saCas9 Nuclease Protein	K044	6.5 µg (50 pmol/50 µL)	$55.00
saCas9 Nuclease Protein (High Concentration)	K144	32.5 µg (250 pmol/25 µL)	$155.00
saCas9 Nuclease NLS Protein	K189	32.5 µg (250 pmol/50 µL)	$155.00
saCas9 Nuclease NLS Protein (Lyophilized)	K152	32.5 µg (250 pmol)	$185.00
CRISPR Kits
Screen It™ CRISPR Cas9 Cleavage Detection Kit	G990	100 Reactions	*
CRISPR Genomic Cleavage Detection Kit	G932	100 Reactions	$170.00
sgRNA Synthesis Kit, spCas9	G520	10 Reactions	*

* Special Introductory Price

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