hPSEN1(WT) Stably Expressing MEF Psen1/2(-/-) Cell Line
|T6439||1x106 cells / 1.0 ml|
|Description||MEF Psen1/2-/- cells were derived from E8.5 embryos which are neomycin and hygromycin-resistant and were immortalized with SV40 large T antigen via transfection with the pMSSVLT plasmid. Human PSEN1 expression was established through retroviral transduction with pMSCV puro hPSEN1WT plasmid and stable expression was determined via puromycin selection. PSEN1 (Presenilin 1) is a gene of interest in neuropathology and diseases such as Alzheimer's disease (AD) in which patients with an inherited form of the disease carry mutations. abm offers a panel of Stable MEF expressing human PSEN1 wildtype and various human PSEN1 mutants for research.|
|Species||Mouse (M. musculus)|
|Applications||For Research Use Only|
|Cell Type||Drug Discovery Cell Lines|
|Expression Profile||Human PSEN1WT Neomycin (G418); hygromycin; and puromycin-resistant|
|Preservation Protocol||1. Freeze Medium: Complete growth medium with 20% FBS and 10% DMSO.|
2. Storage Temperature: Liquid nitrogen vapour phase.
|Unit quantity||1x106 cells / 1.0 ml|
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