Stable 293T-ATD cell line

CAT.NOUNITPRICE
T63401x106 cells / 1.0 ml
$0.00

Specifications


Description

Anti-N-methyl-D-aspartate Receptor Encephalitis (ANRE) is a life threatening autoimmune disease where the body makes antibodies that bind to NMDA receptors (NMDAR) in the brain. This disease manifests as a variety of neurological symptoms including seizures/hallucinations/loss of motor function. The hippocampus and amygdala are the most affected centres of the brain. When anti-NMDAR antibodies bind to NMDA receptors there is a decrease in synaptic currents in the affected neurons. The Stable 293T-ATD cell line expressing NMDAR has been used extensively to uncover the molecular mechanisms that cause ANRE. This cell line would be ideal for research into NMDAR channel function and anti-NMDA antibodies associated with ANRE pathogenesis.

SKUT6340
SpeciesHuman (H. sapiens)
Tissue/Organ/Organ SystemKidney
Cell MorphologyEpithelial
ApplicationsFor Research Use Only
Cell TypeDrug Discovery Cell Lines
Growth PropertiesAdherent
Preservation ProtocolFreeze Medium: Complete growth medium with 20% FBS and 10% DMSO.
2. Storage Temperature: Liquid nitrogen vapour phase
Unit quantity1x106 cells / 1.0 ml
Documents


Supporting Protocol
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