SensiStain™ Anti-EZH2 Antibody
Cat. No. | HY500049 |
Name | SensiStain™ Anti-EZH2 Antibody |
Clone | IHC770 |
Category | IHC Antibodies |
Gene Name | EZH2 |
Gene Full Name | enhancer of zeste homolog 2 (Drosophila) |
Alias | EZH1, ENX-1, KMT6, KMT6A |
Accession Number | BC010858 |
Application | ELISA, IHC |
Raised In | Rabbit |
Clonality | Monoclonal |
Reactivity | Human |
Description |
Enhancer of Zeste Homolog 2 (EZH2) is a methylase of histone H3 that silences gene expression in those regions. It is overexpressed or mutated in gastric, prostate, uterine, breast, and renal cell cancers, as well as in melanoma and most B- and T-cell lymphomas. EZH2 is associated with tumour proliferation and can be used in staining panels to distinguish aggressive lymphomas from less aggressive lymphomas or normal cells. |
Immunogen | Recombinant Protein |
Isotype | IgG |
Uniprot Number | Q15910 |
Recommended Dilutions |
1:50-1:200 |
Storage Buffer | Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
Storage Condition |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. HY500049 |
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