SensiStain™ Anti-p16 Antibody
Cat. No. | HY500021 |
Name | SensiStain™ Anti-p16 Antibody |
Clone | IHC216 |
Category | IHC Antibodies |
Gene Name | p16 |
Application | ELISA, IHC |
Raised In | Mouse |
Clonality | Monoclonal |
Reactivity | Human |
Description |
The p16 (p16INK4A) protein is a cyclin-dependent kinase inhibitor that plays an important regulatory role in the cell cycle. By controlling the transition between the G1 and S phases through regulation of retinoblastoma protein, p16 decelerates cellular differentiation and therefore acts as a tumor suppressor, making it the key marker in several human cancers including head and neck cancer, perianal lesions, melanomas, gliomas, lymphomas, and some types of leukemia. p16 is also clinically indicated in carcinomas of the esophagus, pancreas, lung, biliary tract, liver, colon, and urinary bladder. |
Immunogen | Recombinant Protein |
Isotype | IgG2a, kappa |
Uniprot Number | P42771 |
Recommended Dilutions |
1:50-1:200 |
Storage Buffer | Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide |
Storage Condition |
This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. |
Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. HY500021 |