Anti-Cas9 Antibody

Anti-Cas9 Antibody is an antibody against Cas9, an essential RNA-guided DNA endonuclease observed originally in Streptococcus pyogene among other bacteria and archaea and a component of an adaptive microbial immune system that provides acquired immunity against foreign viruses and plasmids. Cas9 endonuclease is used to cleave double-stranded DNA directed by a short engineered guide-RNA (gRNA), leading to site-directed double strand breaks (DSB) in DNA submstrate. Thus, the CRISPR Cas9 system (clustered regularly interspaced short palindromic repeat CRISPR-associated protein 9) is the latest RNA-guided, endonuclease tool in genome editing which allows for very specific genomic disruption and replacement.

Predicted size of 160kDa.

Working dilution must be determined by the user.

This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20°C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.

abm guarantees that all our Anti-Cas9 Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.