Anti-Histone H4 tetra acetyl Antibody
| Cat. No. | Y051212 |
| Name | Anti-Histone H4 tetra acetyl Antibody |
| Clone | Polyclonal |
| Category | Polyclonal Antibodies |
| Gene Name | Histone H4 |
| Application | WB,ELISA |
| Application Info | The sequence of the immunogen from Tetrahymena hv1 has a high degree of homology to histone H4 in higher organisms. This modification is conserved from yeast to human and a wide range of reactivity is expected. |
| Raised In | Rabbit |
| Clonality | Polyclonal |
| Reactivity | Human |
| Description | Histone H4 is one of the core components of the nucleosome, the basic building block of chromatin. Acetylation of histones is linked to a number of specific processes including transcriptional regulation and genomic organization. |
| Immunogen | Peptide containing the amino terminal region of Tetrahymena histone variant hv1 acetylated at multiple lysines. |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Recommended Dilutions | The sequence of the immunogen from Tetrahymena hv1 has a high degree of homology to histone H4 in higher organisms. This modification is conserved from yeast to human and a wide range of reactivity is expected. |
| Storage Buffer | PBS, pH 7.4 with 0.05% sodium azide. |
| Storage Condition | This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt. |
| Formulation | Liquid |
| Species Reactivity | Human |
| Specificity | The immunogen has a high degree of homology to histone H4, so the antibody primarily recognizes tetra-acetylated histone H4, secondarily recognizes tri-acetylated forms of histone H4. Faint recognition of multiply acetylated histone H2A is observed. |
| Purity | Purified |
| Guarantee | abm guarantees that all our Anti-Histone H4 tetra acetyl Antibody will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement. |
| Material Citation | If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Y051212 |
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- Shimizu, M et al. "Hydrolase controls cellular NAD, sirtuin, and secondary metabolites" Mol Cell Biol 32:3743-55 (2012). PubMed: 22801369.
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