Anti-Myc Tag Antibody (Mouse Monoclonal)

Cat. No.
G019
Unit
100 μg
Price
$175.00
Cat. No. G019
Name Anti-Myc Tag Antibody (Mouse Monoclonal)
Unit 100 μg
Clone Myc.A7
Category Tag Antibodies
Application WB,ELISA,IP,ICC/IF
Raised In Mouse
Clonality Tag
Reactivity Other
Description The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
Immunogen A synthetic peptide corresponding to residues 410-419 (EQKLISEEDL) coupled to KLH.
Isotype IgG1
Concentration 100ug/100ul
Storage Buffer PBS, pH 7.4 with 0.05% sodium azide.
Storage Condition This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20° C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Formulation Liquid
Specificity Myc-tag Monoclonal Antibody. Recognises over-expressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins in transfected mammalian cells.
Guarantee abm guarantees that all our Anti-Myc Tag Antibody (Mouse Monoclonal) will perform as described on this product webpage, if this is not the case we will provide you with a one-time replacement at no extra cost. Documentation and explanation of experiment conducted will be required when submitting a claim for replacement.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. G019
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  • Tattoli, I et al. "Amino Acid Starvation Induced by Invasive Bacterial Pathogens Triggers an Innate Host Defense Program" Cell Host Microbe 11 (6):563-575 (2012). DOI: 10.1016/j.chom.2012.04.012. Application: Western Blot.
  • Müller, I et al. "Ca2+ signaling and gene transcription in glucose-stimulated insulinoma cells" Cell Calcium 52 (2):137-51 (2012). PubMed: 22658828. Application: Immunoblot.
  • Christova, T et al. "Lymphoid enhancer factor-1 mediates loading of Pax3 to a promoter harbouring lymphoid enhancer factor-1 binding sites resulting in enhancement of transcription." Int J Biochem & Cell Biol 42 (5):630-640 (2010). DOI: 10.1007/978-1-61779-455-1_15. Application: Western Blot.
  • Rothenburg, S et al. " Characterization of a ranavirus inhibitor of the antiviral protein kinase PKR" BMC Microbiol 11:56 (2011). DOI: 10.1186/1471-2180-11-56. Application: Western Blot.
  • Shi, XH et al. "The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts" PLoS One 8 (9):e75473 (2013). DOI: 10.1371/journal.pone.0075473. Application: Western Blot.
  • Mo, Y.Y et al. "MicroRNA-145 Suppresses Cell Invasion and Metastasis by Directly Targeting Mucin 1" Journal of Cancer Res 70 (1):278-287 (2010). DOI: 10.1158/0008-5472. Application: Western Blot.
  • Son, O et al. "In vitro and in vivo interaction of AtRma2 E3 ubiquitin ligase and auxin binding protein 1" Biochem Biophys Res Commun 396 (3):492-497 (2010). DOI: 10.1016/j.bbrc.2010.02.032. PubMed: 20152813. Application: Immunoblot.
  • McPherson, VA et al. "Contributions of F-BAR and SH2 domains of Fes protein tyrosine kinase for coupling to the FcεRI pathway in mast cells" Mol Cell Biol 29 (2):389-401 (2008). DOI: 10.1128/MCB.00904-08. Application: Immunostaining.
  • Shi, XH et al. "The expression and localization of N-myc downstream-regulated gene 1 in human trophoblasts" PLoS ONE 8:e75473 (2013). PubMed: 24066183.
  • Zhang, A et al. "The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage" Cell Res. 23(3):340-50 (2013). DOI: 10.1038/cr.2012.164. PubMed: 23208419.
  • Sachdeva, M et al. "MicroRNA-145 suppresses cell invasion and metastasis by directly targeting mucin 1" Cancer Res 70(1):378-87 (2010). DOI: 10.1158/0008-5472.CAN-09-2021. PubMed: 19996288.
  • Sachdeva, M et al. "Negative regulation of miR-145 by C/EBP-β through the Akt pathway in cancer cells" Nucleic Acids Res 40(14):6683-92 (2012). DOI: 10.1093/nar/gks324. PubMed: 22495929.
  • Schmid, D et al. "An abundant, truncated human sulfonylurea receptor 1 splice variant has prodiabetic properties and impairs sulfonylurea action" Cell Mol Life Sci 69:129-48 (2012). PubMed: 21671119.
  • Liu, TT et al. "Rab GTPase regulation of retromer-mediated cargo export during endosome maturation" Mol Biol Cell 23:2505-15 (2012). PubMed: 22593205.
  • Kim, JH et al. "The Arabidopsis RING E3 ubiquitin ligase AtAIRP3, LOG2 participates in positive regulation of high-salt and drought stress responses" Plant Physiol 162:1733-49 (2013). PubMed: 23696092.
  • Petzold, CJ et al. "Cells determine cell density using a small protein bound to a unique tissue-specific phospholipid" PeerJ 1:e192 (2013). PubMed: 24244914.
  • Cho, SK et al. "Arabidopsis PUB22 and PUB23 are homologous U-Box E3 ubiquitin ligases that play combinatory roles in response to drought stress" Plant Cell 20:1899-914 (2008). PubMed: 18664614.
  • Zhu, S et al. "MicroRNA-21 targets tumor suppressor genes in invasion and metastasis" Cell Res 18:350-9 (2008). PubMed: 18270520.
  • Jung, H et al. "Mest, Peg1 inhibits Wnt signalling through regulation of LRP6 glycosylation" Biochem. J. 436:263-9 (2011). PubMed: 21375506. Application: Immunoprecipitation .
  • Ahn, CS et al. "Overexpression of the PP2A regulatory subunit Tap46 leads to enhanced plant growth through stimulation of the TOR signalling pathway" J. Exp. Bot. : (2014). PubMed: 25399018.
  • Su, , B. et al. "A Genome-Wide RNAi Screen Identifies FOXO4 as a Metastasis-Suppressor through Counteracting PI3K/AKT Signal Pathway in Prostate Cancer" Plos One 9 (7): (2014). PubMed: 24983969.
  • Jo, H et al. "Erythropoietin and carbamylated erythropoietin promote histone deacetylase 5 phosphorylation and nuclear export in rat hippocampal neurons" Biochemical and Biophysical Research Communications 1(470):220-225 (2016). DOI: 10.1016/j.bbrc.2016.01.039. Application: Western Blot.
  • Min, H. J., Cui, L. H., Oh, T. R., Kim, J. H., Kim, T. W., & Kim, W. T. "Os BZR 1 turnover mediated by Os SK 22‐regulated U‐box E3 ligase Os PUB 24 in rice BR response" The Plant Journal 99(3):426-438 (2019).
  • Singh, R., Dangol, S., Chen, Y., Choi, J., Cho, Y. S., Lee, J. E., ... & Jwa, N. S. "Magnaporthe oryzae effector AVR-Pii helps to establish compatibility by inhibition of the rice NADP-malic enzyme resulting in disruption of oxidative burst and host innate immunity"  Molecules and cells  39(5):426 (2016).
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