DJ-1 CRISPR Stable Knockout HeLa Cell Line

T61811x106 cells / 1.0 ml


DescriptionDJ-1 CRISPR Stable Knockout HeLa Cell line was established using the CRISPR/Cas9 system and validated by immunoblotting with anti-DJ-1 antibody and by genomic DNA sequencing. The functions of DJ-1 are not yet fully understood though studies show that the protein may play a role in mitigating oxidative stress particularly in brain cells. It is also thought that DJ-1 may act as a chaperone protein. Mutations in PARK7 the gene encoding the DJ-1 protein are associated with early-onset Parkinson disease. This cell line is suitable for research regarding the functions of DJ-1 including its role in the development of Parkinson disease.
SpeciesHuman (H. sapiens)
Tissue/Organ/Organ SystemCervix
Cell MorphologyEpithelial-like
ApplicationsFor Research Use Only
Seeding Density40,000 - 50,000 cells/cm2
Population Doubling Time24 - 34 hours
Cell TypeDrug Discovery Cell Lines
Growth PropertiesAdherent
Expression ProfileGenomic DJ-1 knock-out
Unit quantity1x106 cells / 1.0 ml
QC1) Immunoblotting; 2) Genomic DNA sequencing; 3) STR

Supporting Protocol




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