DJ-1 CRISPR Stable Knockout HeLa Cell Line
|T6181||1x106 cells / 1.0 ml|
|Description||DJ-1 CRISPR Stable Knockout HeLa Cell line was established using the CRISPR/Cas9 system and validated by immunoblotting with anti-DJ-1 antibody and by genomic DNA sequencing. The functions of DJ-1 are not yet fully understood though studies show that the protein may play a role in mitigating oxidative stress particularly in brain cells. It is also thought that DJ-1 may act as a chaperone protein. Mutations in PARK7 the gene encoding the DJ-1 protein are associated with early-onset Parkinson disease. This cell line is suitable for research regarding the functions of DJ-1 including its role in the development of Parkinson disease.|
|Species||Human (H. sapiens)|
|Applications||For Research Use Only|
|Seeding Density||40,000 - 50,000 cells/cm2|
|Population Doubling Time||24 - 34 hours|
|Cell Type||Drug Discovery Cell Lines|
|Expression Profile||Genomic DJ-1 knock-out|
|Unit quantity||1x106 cells / 1.0 ml|
|QC||1) Immunoblotting; 2) Genomic DNA sequencing; 3) STR|
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