Recombinant Human CXCL1 (E. coli)

Cat. No.
Z100285
Unit
Price
$89.00
Cat. No. Z100285
Name Recombinant Human CXCL1 (E. coli)
Description A chemokine, the growth regulated oncogene-alpha is identical with MGSA (melanoma growth stimulatory activity) with its new designation being CXCL1. The expression of GRO can be induced by serum or PDGF and/or by a variety of inflammatory mediators, such as IL-1 and TNF, in monocytes, fibroblasts, melanocytes and epithelial cells. In certain tumor cell lines, GRO is expressed constitutively. Similar to other alpha chemokines, the three GRO proteins are potent neutrophil attractants and activators. In addition, these chemokines are also active toward basophils. All three GROs can bind with high affinity to the IL-8 receptor type B.
Organism Human (H. sapiens)
Unit quantity 25 µg
Family Chemokine-alpha Family (CXC)
Aliases

Growth Regulated Protein, Melanoma Growth Stimulatory Activity, GRO-alpha, MGSA-alpha, CXCL1, NAP-3, GRO1, C-X-C motif chemokine 1, GRO-alpha(1-73)
Recombinant Human Growth Regulated Alpha Protein (CXCL1)

Gene Symbol CXCL1
Gene ID 2919
Accession Number P09341
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 8 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 μm filtered solution in 40 mM NaCl and PB, pH 7.0
Function Determined by the ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/mL
Reconstitution

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100285
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