Recombinant Human CXCL11 (E. coli)

Cat. No.
Cat. No. Z100585
Name Recombinant Human CXCL11 (E. coli)
Description The CXCL11 belongs to the CXC chemokine family characterized by the presence of one amino acid in between the two NH2-terminal cysteines. CXCL11 is produced by a variety of cells including leukocytes, fibroblasts, and endothelial cells upon stimulation with interferons (IFNs). Simultaneous stimulation of fibroblasts or endothelial cells with IFN-gamma and Interleukin-1b or the TLR3 ligand double-stranded RNA results in a synergistic increase of CXCL11 production. CXCL11 attracts natural killer cells and activated T-helper 1 cells. Like CXCL9 and CXCL10, CXCL11 signals through CXC chemokine receptor 3 (CXCR3).
Organism Human (H. sapiens)
Unit quantity 20 µg
Family Chemokine-alpha Family (CXC)
Aliases CXCL11, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11
Recombinant Human IFN-Inducible T-cell Chemoattractant (CXCL11)
Gene Symbol CXCL11
Gene ID 6373
Accession Number O14625
Source E. coli
Species Human (H. sapiens)
Appearance Lyophilized Powder
Molecular Weight 8 kDa
Endotoxin Level <1.0 EU/µg of recombinant protein as determined by the LAL method
Purity >95% as determined by SDS-PAGE
Formulation Lyophilized from a 0.2 μm filtered solution in PB,100 mM NaCl pH 7.5
Function Determined by its ability to chemoattract human T cells using a concentration range of 2.0-10.0 ng/mL
Reconstitution A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.
Storage The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.
Usage For research use only. Not for diagnostic or therapeutic use.
Material Citation If use of this material results in a scientific publication, please cite the material in the following manner: Applied Biological Materials Inc, Cat. No. Z100585
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Controls and Related Product:

1.0 mg

50 µg

50 µg

10 µg